"MRP1" Related Products

Mouse Anti-Human MRP1 Monoclonal Antibody

Cat. No.: CAB-905MH
Specificity: Human multidrug resistanec-associated protein 1
Host: Mouse
Clonality: Monoclonal
Positive Control: Breast tumors
Staining Pattern: Cytoplasmic, Cell membrane
Specificity Note: The MRP molecule, an integral membrane glycophosphoprotein belonging to the same superfamily of ATP-binding cassette transmembrane transporter proteins as P-glycoprotein, is overexpressed in many P-glycoprotein-negative, multidrug resistant cell lines and tumours. It is believed that the main function of MRP in drug resistance is that of a plasma membrane drug efflux pump.
Applications: Formalin-fixed paraffin-embedded tissue, or IHC frozen sections. No antigen retrieval necessary.
Recommended Usage: IHC test, research use only. Incubate with samples at RT for 60min or at 4℃ overnight.
Storage: 2-8℃ for 12 months.
Gene Name: MRP1 Multidrug resistance-associated protein-1 [ Homo sapiens ]
Synonyms: MRP1; ATP-binding cassette, sub-family C (CFTR/MRP), member 1; MRP; multidrug resistance associated protein 1; GS-X; Leukotriene C(4) transporter; ATP-binding cassette sub-family C member 1; multidrug resistance-associated protein 1; multiple drug resistance-associated protein; ABC29; ABCC; DKFZp781G125; multiple drug resistance protein 1; DKFZp686N04233; multidrug resistance protein
Gene ID: 4363
mRNA Refseq: NM_004996.3
Protein Refseq: NP_004987.2
MIM: 158343
UniProt ID: P33527
Chromosome Location: 16p13.1
Function: ATP binding;ATPase activity;ATPase activity, coupled to transmembrane movement of substances;hydrolase activity;nucleotide binding;transporter activity

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Optional requirements on this protein    +Expand
C-fusion    N-fusion   Non-tagged
His    GST   Fc   Others
<1.0 eu/μg    <0.1 eu/μg   <0.01 eu/μg   Not required
Monomer Isolation    Dimer Isolation    Not required
>80% by SDS-PAGE    >90% by SDS-PAGE   >95% by SDS-PAGE   Others

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