Mouse Anti-Human MRP1 Monoclonal Antibody
Cat.No. : | CAB-905MH |
- Specification
- Gene Information
- Related Products
Cat. No. : | CAB-905MH |
Specificity : | Human multidrug resistanec-associated protein 1 |
Host : | Mouse |
Clonality : | Monoclonal |
Positive Control : | Breast tumors |
Staining Pattern : | Cytoplasmic, Cell membrane |
Specificity Note : | The MRP molecule, an integral membrane glycophosphoprotein belonging to the same superfamily of ATP-binding cassette transmembrane transporter proteins as P-glycoprotein, is overexpressed in many P-glycoprotein-negative, multidrug resistant cell lines and tumours. It is believed that the main function of MRP in drug resistance is that of a plasma membrane drug efflux pump. |
Applications : | Formalin-fixed paraffin-embedded tissue, or IHC frozen sections. No antigen retrieval necessary. |
Recommended Usage : | IHC test, research use only. Incubate with samples at RT for 60min or at 4℃ overnight. |
Storage : | 2-8℃ for 12 months. |
Gene Name : | MRP1 Multidrug resistance-associated protein-1 [ Homo sapiens ] |
Synonyms : | MRP1; ATP-binding cassette, sub-family C (CFTR/MRP), member 1; MRP; multidrug resistance associated protein 1; GS-X; Leukotriene C(4) transporter; ATP-binding cassette sub-family C member 1; multidrug resistance-associated protein 1; multiple drug resistance-associated protein; ABC29; ABCC; DKFZp781G125; multiple drug resistance protein 1; DKFZp686N04233; multidrug resistance protein |
Gene ID : | 4363 |
mRNA Refseq : | NM_004996.3 |
Protein Refseq : | NP_004987.2 |
MIM : | 158343 |
UniProt ID : | P33527 |
Chromosome Location : | 16p13.1 |
Function : | ATP binding;ATPase activity;ATPase activity, coupled to transmembrane movement of substances;hydrolase activity;nucleotide binding;transporter activity |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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