Recombinant Equine Small Inducible Cytokine A5 RANTES

• Cat.No.: LOC100033925-141E
• Product Overview: Recombinant Equine CCL5 protein was expressed inYeastand purified by using Ion-exchange chromatography, 7.9 kDa (68 aa).

Specification

• Cat. No.: LOC100033925-141E
• Description: CCL5 is an 8kDa protein classified as a chemotactic cytokine or chemokine. CCL5 is chemotactic for T cells, eosinophils, and basophils, and plays an active role in recruiting leukocytes into inflammatory sites. With the help of particular cytokines (i.e., IL-2 and IFN-γ) that are released by T cells, CCL5 also induces the proliferation and activation of certain natural-killer (NK) cells to form CHAK (CC-Chemokine-activated killer) cells.
• Source: Yeast.
• Sequences Of Amino Acids: SPYASDTTPC CFAYISRPLP RAHIQEYFYT SSKCSIPAVV FVTRKKRQVC ANPEKKWVRE YINTLEMS.
• Formulation/Reconstitution: Lyophilized. Reconstitute with sterile phosphate-buffered saline containing at least 0.1% carrier protein.
• Purity: >95% as visualized by SDS-PAGE analysis.
• Purification: Ion-exchange chromatography.
• Biological Activity: In testing.
• Storage: Stable for up to twelve months from date of receipt at -20°C. Stable for at least 3 months when stored in working aliquots with a carrier protein at -20°C. Avoid repeated freeze/thaw cycles.
• Pathways: Chemokine signaling pathway; Cytokine-cytokine receptor interaction; Cytosolic DNA-sensing pathway; NOD-like receptor signaling pathway; Prion diseases; Toll-like receptor signaling pathway

Gene Information

• Gene Name: LOC100033925 small inducible cytokine A5 RANTES [ Equus caballus ]
• Synonyms: LOC100033925; small inducible cytokine A5 RANTES; CCL5; RANTES; C-C motif chemokine 5; small-inducible cytokine A5; T-cell-specific protein RANTES
• Gene ID: 100033925
• mRNA Refseq: NM_001081863
• Protein Refseq: NP_001075332
• UniProt ID: Q8MKD0
• Chromosome Location: 11