Active Native Human GPT
Cat.No. : | GPT-1840H |
Product Overview : | Native Human GPT was prepared from Human Liver. CAS# 9000-86-6. |
- Specification
- Gene Information
- Related Products
Description : | This gene encodes cytosolic alanine aminotransaminase 1 (ALT1); also known as glutamate-pyruvate transaminase 1. This enzyme catalyzes the reversible transamination between alanine and 2-oxoglutarate to generate pyruvate and glutamate and, therefore, plays a key role in the intermediary metabolism of glucose and amino acids. Serum activity levels of this enzyme are routinely used as a biomarker of liver injury caused by drug toxicity, infection, alcohol, and steatosis. A related gene on chromosome 16 encodes a putative mitochondrial alanine aminotransaminase. |
Source : | Human Liver |
Species : | Human |
Form : | Lyophilized. Homodimer. |
Bio-activity : | >5 U/mg (Dimension® Clinical Chemistry System) |
Molecular Mass : | 57,903.6 based on the sequence |
Purity : | ≥0.5 mg protein/mg (Coomassie) |
Unit Definition : | One unit will catalyze the transamination of one micromole of L-alanine to alpha-ketoglutarate, forming L-glutamate and pyruvate per minute at 37°C and pH 7.8. Measured at 340 nm as one equimolar amount of NAD produced by a coupled reaction. |
Applications : | Diagnostic Controls, Calibrators Standards; Clinical Chemistry; Testing/Assay Validation; Life Science; Manufacturing |
Storage : | -20°C |
Gene Name : | GPT glutamic-pyruvate transaminase (alanine aminotransferase) [ Homo sapiens ] |
Official Symbol : | GPT |
Synonyms : | GPT; glutamic-pyruvate transaminase (alanine aminotransferase); alanine aminotransferase 1; ALT1; GPT1; GPT 1; glutamic-alanine transaminase 1; glutamic--alanine transaminase 1; glutamic--pyruvic transaminase 1; glutamate pyruvate transaminase 1; AAT1; |
Gene ID : | 2875 |
mRNA Refseq : | NM_005309 |
Protein Refseq : | NP_005300 |
MIM : | 138200 |
UniProt ID : | P24298 |
Chromosome Location : | 8q24.2-qter |
Pathway : | Alanine and aspartate metabolism, organism-specific biosystem; Alanine, aspartate and glutamate metabolism, organism-specific biosystem; Alanine, aspartate and glutamate metabolism, conserved biosystem; Amino acid synthesis and interconversion (transamination), organism-specific biosystem; Metabolic pathways, organism-specific biosystem; Metabolism, organism-specific biosystem; Metabolism of amino acids and derivatives, organism-specific biosystem; |
Function : | 1-aminocyclopropane-1-carboxylate synthase activity; L-alanine:2-oxoglutarate aminotransferase activity; L-alanine:2-oxoglutarate aminotransferase activity; pyridoxal phosphate binding; transaminase activity; |
Products Types
◆ Recombinant Protein | ||
GPT-1785R | Recombinant Rhesus Macaque GPT Protein, His (Fc)-Avi-tagged | +Inquiry |
GPT-5304H | Recombinant Human GPT Protein, GST-tagged | +Inquiry |
GPT-2236H | Recombinant Human GPT Protein, MYC/DDK-tagged | +Inquiry |
Gpt-374M | Recombinant Mouse Gpt Protein, His-tagged | +Inquiry |
GPT-2330R | Recombinant Rat GPT Protein, His (Fc)-Avi-tagged | +Inquiry |
◆ Native Protein | ||
GPT-189P | Active Native Porcine GPT protein | +Inquiry |
GPT-187H | Active Native Human Glutamate Pyruvate Transaminase | +Inquiry |
GPT-188S | Active Native Swine Glutamate Pyruvate Transaminase | +Inquiry |
◆ Lysates | ||
GPT-721RCL | Recombinant Rat GPT cell lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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