Native Bovine Pancreatic Trypsin Inhibitor

• Cat.No.: PTI-1900B
• Product Overview: Native Bovine is purifiedBovine lung.

Specification

• Cat. No.: PTI-1900B
• Description: PTI is a natural proteinase inhibitorpolypeptide consisting of fifty-eight amino acids arranged in a single polypeptidechain, cross-linked by three disulfide bridges and having a MW of 6.512 kDa.
• Source: Bovine lung
• Species: Bovine
• Form: Aprotinin (1 mg/ml)was lyophilized with no additives.
• Purity: Greater than 98.0%as determined by: Analysis by RP-HPLC, anion-exchange FPLC, and analysis byreducing and non-reducing SDS-PAGE Silver Stained gel.
• Endotoxin: Less than 0.1 ng/ug(1 EU/ug) of PTI.
• Biological activity: PTI activitywas found to be 6 x 10⁶ IU/mg.
• Storage: LyophilizedAprotinin although stable at room temperature for 3 weeks, should be storeddesiccated below -18°C. Upon reconstitution Aprotinin should be stored at 4°Cbetween 2-7 days and for future use below -18°C. For long term storage it isrecommended to add a carrier protein (0.1% HSA or BSA). Avoid freeze-thawcycles.
• OfficialSymbol: PTI

Gene Information

• Gene Name: PTI pancreatic trypsininhibitor [ Bos taurus ]
• Synonyms: PTI; pancreatictrypsin inhibitor; BPI; BPTI; pancreatic trypsin inhibitor; aprotinin; basicprotease inhibitor
• Gene ID: 404172
• mRNA Refseq: NM_001001554
• Protein Refseq: NP_001001554
• UniProt ID: P00974
• Chromosome Location: 13
• Pathway: Axon guidance; Developmental Biology;Glypican 1 network; NCAM signaling for neurite out-growth; NCAM1interactions; Prion diseases
• Function: peptidase inhibitor activity; potassiumchannel inhibitor activity; serine-type endopeptidase inhibitor activity