Recombinant Rat Plasminogen Activator, Urokinase
Cat.No. : | Plau-1297R |
Product Overview : | RecombinantRat High Molecular Weight two-chain Plau. |
- Specification
- Gene Information
- Related Products
Cat. No. : | Plau-1297R |
Description : | Plauisan enzyme that in humans is encoded by the Plau gene. This gene encodes aserine protease involved in degradation of the extracellular matrix andpossibly tumor cell migration and proliferation. A specific polymorphism inthis gene may be associated with late-onset Alzheimer disease and also withdecreased affinity for fibrin-binding. The protein encoded by this geneconverts plasminogen to plasmin by specific cleavage of an Arg-Val bond inplasminogen. This gene"s proprotein is cleaved at a Lys-Ile bond by plasminto form a two-chain derivative in which a single disulfide bond connects theamino-terminal A-chain to the catalytically active, carboxy-terminal B-chain. |
Source : | Insect cells |
Species : | Human |
Formulation : | Frozen liquid in 0.05M Sodium Acetate+0.1M NaCI+1mM EDTA, pH 5.0. |
Molecular Weight : | 44.0 kDa |
Concentration : | 2.0 mg/mL |
Storage : | Store in workingaliquots at -80°C. Avoid repeated freeze-thaw cycles. |
OfficialSymbol : | Plau |
Gene Name : | Plauplasminogen activator, urokinase [ Rattus norvegicus ] |
Synonyms : | Plau; plasminogenactivator, urokinase; UPAM; MGC124931; urokinase-typeplasminogen activator; uPA; U-plasminogen activator; Urinary plasminogenactivator, urokinase |
Gene ID : | 25619 |
mRNA Refseq : | NM_013085 |
Protein Refseq : | NP_037217 |
UniProt ID : | Q3KR76 |
Chromosome Location : | 15p16 |
Pathway : | BloodClotting Cascade; Complement and Coagulation Cascades; Complement andcoagulation cascades; Dissolution of Fibrin Clot; Endochondral Ossification;Hemostasis; Wnt Signaling Pathway; Wnt Signaling Pathway and Pluripotency |
Function : | kinase activity; peptidase activity; serine-typeendopeptidase activity |
Products Types
◆ Recombinant Protein | ||
PLAU-1868H | Recombinant Human PLAU Protein, MYC/DDK-tagged | +Inquiry |
PLAU-806H | Recombinant Human PLAU Protein | +Inquiry |
PLAU-6811M | Recombinant Mouse PLAU Protein, His (Fc)-Avi-tagged | +Inquiry |
Plau-4908M | Recombinant Mouse Plau Protein, Myc/DDK-tagged | +Inquiry |
PLAU-1697H | Recombinant Human PLAU Protein, His (Fc)-Avi-tagged | +Inquiry |
◆ Native Protein | ||
PLAU-31777TH | Native Human Human SERPINE1 | +Inquiry |
PLAU-31687TH | Native Human PLAU | +Inquiry |
PLAU-22H | Native Human PLAU protein | +Inquiry |
◆ Lysates | ||
PLAU-1734HCL | Recombinant Human PLAU cell lysate | +Inquiry |
◆ Assay kits | ||
Kit-0702 | PLAU (Human) Chromogenic Activity Assay Kit (Direct Assay) | +Inquiry |
Kit-0703 | PLAU (Human) Chromogenic Activity Assay Kit (Indirect Assay) | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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