Active Recombinant Human Lysyl Oxidase-Like 3, His-tagged
Cat.No. : | LOXL3-1979H |
Product Overview : | RecombinantHuman LOXL3 protein was expressed in Chinese HamsterOvary cell line. Met1-Ile753, with a C-terminal 10-Histag. |
- Specification
- Gene Information
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Cat. No. : | LOXL3-1979H |
Description : | LOXL3 is asecreted copper amine oxidase. The N-terminal region of LOXL3 contains fourscavenger receptor cysteinerich (SRCR) domains. The C-terminal regionconsists of a catalytic domain similar to other lysyl oxidases and a cytokinereceptor-like domain. The catalytic domain contains conserved residues requiredfor copper binding and formation of a lysyl tyrosylquinone cofactor. LOXL3 isexpressed primarily in epidermis, kidney, aorta, and chondrocytes. The enzymeis expressed at low levels in most other tissues. Like lysyl oxidase, LOXL3oxidizes the lysine ε-amino groups of a number of collagen substrates, and isalso active against other primary amines. However, LOXL3 does not requireproteolytic processing to be activated. |
Source : | Chinese HamsterOvary cell line, CHO-derived. |
Form : | Supplied as a 0.2 μmfiltered solution in MES and NaCl. |
N-terminalSequence : | Ser26 |
MolecularWeight : | 82 kDa |
Activity : | Measuredby its ability to produce hydrogen peroxide during the oxidation of benzylamine.The specific activity is > 1.5 pmoles/min/μg, as measured under the describedconditions. |
Endotoxin Level : | <1.0EU per 1μg of the protein by the LAL method. |
SDS-PAGE : | 90-100kDa, reducing conditions. |
Purity : | >90%,by SDS-PAGE under reducing conditions and visualized by Colloidal CoomassieBlue stain at 5 μg per lane. |
Storage : | Use amanual defrost freezer and avoid repeated freezethaw cycles. 6 monthsfrom date of receipt, -20 to -70°C as supplied. 3 months,-20to-70°C under sterile conditions after opening. |
Gene Name : | LOXL3 lysyl oxidase-like 3 [ Homosapiens ] |
Official Symbol : | LOXL3 |
Synonyms : | LOXL3; lysyloxidase-like 3; LOXL; lysyl oxidase homolog 3; lysyl oxidase-likeprotein 3; EC 1.4.3.13 |
Gene ID : | 84695 |
mRNA Refseq : | NM_032603 |
Protein Refseq : | NP_115992 |
MIM : | 607163 |
UniProt ID : | P58215 |
Chromosome Location : | 2p13 |
Function : | copper ion binding;metal ion binding; oxidoreductase activity; oxidoreductase activity, actingon the CH-NH2 group of donors, oxygen as acceptor; protein-lysine 6-oxidaseactivity; scavenger receptor activity |
Products Types
◆ Recombinant Protein | ||
LOXL3-277H | Recombinant Human LOXL3 Protein, His-tagged | +Inquiry |
LOXL3-4730H | Recombinant Human LOXL3 Protein, GST-tagged | +Inquiry |
LOXL3-5133M | Recombinant Mouse LOXL3 Protein, His (Fc)-Avi-tagged | +Inquiry |
Loxl3-278M | Recombinant Mouse Loxl3 Protein, His-tagged | +Inquiry |
LOXL3-1419H | Recombinant Human LOXL3 protein, His-GST-tagged | +Inquiry |
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For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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