Recombinant Human HTR2A, GST-tagged
Cat.No. : | HTR2A-1872H |
Product Overview : | RecombinantHuman HTR2A, expressed as gst-tagged fusion protein by E.Coli is purified byGSH-sepharose. |
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Cat. No. : | HTR2A-1872H |
Description : | This gene encodes one ofthe receptors for serotonin, a neurotransmitter with many roles. Mutations inthis gene are associated with susceptibility to schizophrenia andobsessive-compulsive disorder, and are also associated with response to theantidepressant citalopram in patients with major depressive disorder (MDD).MDD patients who also have a mutation in intron 2 of this gene show asignificantly reduced response to citalopram as this antidepressantdownregulates expression of this gene. Multiple transcript variants encodingdifferent isoforms have been found for this gene |
Source : | E. coli. |
Storage buffer : | 1M PBS (58mM Na2HPO4,17mM NaH2PO4, 68mM NaCl,pH8. ) added with 100mM GSH and 1% Triton X-100,15%glycerol. |
Gene Name : | HTR2A 5-hydroxytryptamine(serotonin) receptor 2A, G protein-coupled [ Homo sapiens ] |
Synonyms : | 5-hydroxytryptamine(serotonin) receptor 2A;G protein-coupled;HTR2; 5-HT2A;-hydroxytryptaminereceptor 2A;5-hydroxytryptaminereceptor 2A;5-HT-2A;5-HT2 receptor;serotonin5-HT-2A receptor; 5-hydroxytryptamine (serotonin) receptor 2A; 5-HT2A; Serotonin receptor2A; 5-HT-2; 5 HT 2; 5HT 2A; 5 HT2 receptor; 5 HT2A; 5 hydroxytryptamine receptor 2A; 5-HT-2;5-HT-2A; 5-hydroxytryptamine 2A receptor; 5-hydroxytryptamine receptor 2A;5HT2A_HUMAN; HTR 2; HTR2; HTR2A; OTTHUMP00000018378; HTR2; |
Gene ID : | 3356 |
mRNA Refseq : | NM_000621 |
Protein Refseq : | NP_000612 |
MIM : | 182135 |
UniProt ID : | P28223 |
Chromosome Location : | 13q14-q21 |
Pathway : | Adherensjunction; Calciumsignaling pathway; Calciumsignaling pathway; Class A/1(Rhodopsin-like receptors); G alpha (q)signalling events; GPCRdownstream signaling, GPCR ligandbinding; GPCRs; GPCRs |
Function : | 1-(4-iodo-2,5-dimethoxyphenyl)propan-2-aminebinding; G-proteincoupled receptor activity; drugbinding;hosphatidylinositolphospholipase C activity;receptoractivity;serotoninbinding;serotoninreceptor activity;signaltransducer activity |
Products Types
◆ Recombinant Protein | ||
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HTR2A-4374M | Recombinant Mouse HTR2A Protein, His (Fc)-Avi-tagged | +Inquiry |
HTR2A-1996R | Recombinant Rhesus Macaque HTR2A Protein, His (Fc)-Avi-tagged | +Inquiry |
HTR2A-7932M | Recombinant Mouse HTR2A Protein | +Inquiry |
◆ Assay kits | ||
Kit-1352 | HTR2A U2OS β-Arrestin GPCR Assay Kit | +Inquiry |
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For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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