Address: 45-1 Ramsey Road, Shirley, NY 11967, USA    USA: 1-631-559-9269  1-631-448-7888   Fax: 1-631-938-8127  Europe: 44-207-048-3343   Email:
Home > Products > Antibody > Monoclonal Antibodies > Rabbit Anti-Rat KIM-1 / TIM1 / HACVR1 Monoclonal Antibody

Rabbit Anti-Rat KIM-1 / TIM1 / HACVR1 Monoclonal Antibody

"Havcr1" Related Products.
By Species
+Expand -Collapse
By Source
+Expand -Collapse
By Tag
Product Overview:
Rabbit Monoclonal Antibody to Rat KIM-1 / TIM1 / HACVR1
Antigen Description:
Mouse hepatitis A virus cellular receptor 1 (HAVCR1), also known as T cell immunoglobulin and mucin domain-containing protein 1(TIMD1)and T cell membrane protein 1(TIM1), is a member of the TIM family , an immunologically important group of receptors that is conserved in vertebrates. TIM1 is widely expressed with highest levels in kidney and testis. It has been shown that mouse HAVCR1 is expressed by stimulated T-cells during primary antigen stimulation and associates with immunomodulatory properties. TIM1 is a type 1 integral membrane glycoprotein, and in the ECD contains one V-type I?g-like domain extended above the cell surface by a mucin-like domain characterized by a variable number of threonine, serine, and proline (TSP) hexameric repeats. Extensive O-linked glycosylation resulted in the 70-80 kDa molecular mass more higher than the calculated MW(33KDa). TIM1 plays a critical role in T-helper cell development and the regulation of asthma and allergic diseases. In addition to HAV, another identified ligand for TIM1 is TIMD4. Mouse TIM1 ECD shares 50% and 80% amino acid sequence homology with human and rat TIM1 ECD rexpectively.
Rat KIM-1 / TIM1 / HACVR1. No cross-reactivity in ELISA with Mouse KIM-1 / TIM1, Human KIM-1 / TIM1, Human TIMD3, Human cell lysate ( 293 cell line )
Recombinant Rat KIM-1 / TIM1 / HAVCR1 Protein
Rabbit IgG
Cross Reactivity:
Western blot: This antibody can be used at 1-2 μg/mL with the appropriate secondary reagents to detect rat KIM1 in WB. Using a DAB detection system, the detection limit for rat KIM1 is approximately 0.125 ng/lane under non-reducing conditions and 0.25 ng/lane under reducing conditions.ELISA: This antibody can be used at 0.1-0.2 μg/mL with the appropriate secondary reagents to detect rat KIM1. The detection limit for rat KIM1 is approximately 0.00975 ng/well.
This antibody was obtained from a rabbit immunized with purified, human cell-derived, recombinant Rat
0.2 μm filtered solution in PBS with 5% trehalose
This antibody can be stored at 2-8 °C for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20 to -70 °C. Preservative-Free.Sodium azide is recommended to avoid contamination (final concentration 0.05%-0.1%). It is toxic to cells and should be disposed of properly. Avoid repeated freeze-thaw cycles.

Online Inquiry    
Note: There will be extra charge for optional service!
Optional requirements on this protein +Expand
C-fusion   N-fusion  Non-tagged
His   GST  Fc  Others
<1.0 eu/μg   <0.1 eu/μg  <0.01 eu/μg  Not required
Monomer Isolation   Dimer Isolation   Not required
>80% by SDS-PAGE   >90% by SDS-PAGE  >95% by SDS-PAGE  Others
Please input "biomart" as verification code.
Please review Creative Biomart's privacy policy for more information.
Price does not include shipping and packaging costs.Request quote for final price.

If you have any other questions, please call

online inquiry

Welcome! For price inquiries, please feel free to contact us through the form below. We will get back to you as soon as possible.

45-1 Ramsey Road, Shirley, NY 11967, USA
USA: 1-631-559-9269  1-631-448-7888
Europe: 44-207-048-3343
FAX: 1-631-938-8127

facebook twitter linkedin google plus google plus

Join 10 other subscribers

Easy access to products and services you need from our library via powerful searching tools
Copyright © 2007 - 2016 Creative Biomart. All Rights Reserved.