Address: 45-1 Ramsey Road, Shirley, NY 11967, USA    USA: 1-631-559-9269  1-631-448-7888   Fax: 1-631-938-8127  Europe: 44-207-048-3343   Email: info@creative-biomart.com
Home > Products > Antibody > Monoclonal Antibodies > Rabbit Monoclonal Antibody to Human Nephroblastoma Overexpressed

Rabbit Monoclonal Antibody to Human Nephroblastoma Overexpressed

   Share
"NOV" Related Products.
By Species
+Expand -Collapse
By Source
+Expand -Collapse
By Tag
His(8)
N/A(2)
T7/His(1)
Cat.No.:
CAB11588RH
Product Overview:
Rabbit Monoclonal Antibody to Human Nephroblastoma Overexpressed
Antigen Description:
Protein NOV homolog, also known as Nephroblastoma-overexpressed gene protein homolog, NOV, and CCN3, is secreted protein which belongs to the?CCN family. CCN3 expression was observed in a broad variety of tissues from the early stage of development. It contains one?CTCK (C-terminal cystine knot-like) domain, one?IGFBP N-terminal domain, one?TSP type-1 domain, and one?VWFC domain. CCN3, a founding member of the CCN family of growth regulators, was linked with hematology in 2003 when it was detected in human serum. CCN3 acts through the core stem cell signalling pathways including Notch and Bone Morphogenic Protein, connecting CCN3 with the modulation of self-renewal and maturation of a number of cell lineages including hematopoietic, osteogenic and chondrogenic. Altered CCN3 expression is associated with numerous solid tumors including glioblastoma, melanoma, adrenocortical tumours, prostate cancer and bone malignancies including osteosarcoma. CCN3 may affect the extracellular environment of the niche for hematopoietic stem cells. CCN3 has emerged as a key player in stem cell regulation, hematopoiesis and a crucial component within the bone marrow microenvironment.
Specificity:
Human CCN3 / NOV / IGFBP9. No cross-reactivity in ELISA with Human WISP1; Human cell lysate (293 cell line)
Immunogen:
Recombinant Human CCN3 / NOV / IGFBP9 Protein
Host:
Rabbit
Isotype:
Rabbit IgG
Species:
Human
Clone:
A131
Applications:
Western blot; ELISA
Dilution:
Western blot: This antibody can be used at 1-2 μg/mL with the appropriate secondary reagents to detect Human NOV in WB.Direct ELISA: This antibody can be used at 0.1-0.2 μg/mL with the appropriate secondary reagents to detect Human NOV. The detection limit for Human NOV is approximately 0.00975 ng/well.
Preparation:
This antibody was obtained from a rabbit immunized with purified, human cell-derived, recombinant Human CCN3 / NOV / IGFBP9
Format:
0.2 μm filtered solution in PBS with 5% trehalose
Storage:
This antibody can be stored at 2-8°C for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20 to -70 °C. Preservative-Free.Sodium azide is recommended to avoid contamination (final concentration 0.05%-0.1%). It is toxic to cells and should be disposed of properly. Avoid repeated freeze-thaw cycles.


Online Inquiry    
Note: There will be extra charge for optional service!
Optional requirements on this protein +Expand
C-fusion   N-fusion  Non-tagged
His   GST  Fc  Others
<1.0 eu/μg   <0.1 eu/μg  <0.01 eu/μg  Not required
Monomer Isolation   Dimer Isolation   Not required
>80% by SDS-PAGE   >90% by SDS-PAGE  >95% by SDS-PAGE  Others
Please input "biomart" as verification code.
Please review Creative Biomart's privacy policy for more information.
Price does not include shipping and packaging costs.Request quote for final price.

If you have any other questions, please call
+1-631-559-9269.

online inquiry

Welcome! For price inquiries, please feel free to contact us through the form below. We will get back to you as soon as possible.

45-1 Ramsey Road, Shirley, NY 11967, USA
USA: 1-631-559-9269  1-631-448-7888
Europe: 44-207-048-3343
FAX: 1-631-938-8127
EMAIL: info@creative-biomart.com

facebook twitter linkedin google plus google plus

Join 10 other subscribers

24x7
CUSTOMER SERVICE
Easy access to products and services you need from our library via powerful searching tools
Copyright © 2007 - 2016 Creative Biomart. All Rights Reserved.