Active Recombinant Human RIPK2, GST-tagged
Cat.No. : | RIPK2-1479H |
Product Overview : | Recombinant human RIPK2 (1-299) was expressed by baculovirus in Sf9 insect cells using a N-terminal GST tag. |
- Specification
- Gene Information
- Related Products
Description : | RIPK2 (RIP2; RICK) is a death domain-containing protein kinase encoding a predicted 540-amino acid protein which contains an N-terminal serine/threonine kinase catalytic domain and a C-terminal caspase activation and recruitment domain. RIPK2 is thought to regulate apoptosis induced by the FAS receptor pathway. RIPK2 has been shown to specifically interact with the CARD of ICE/caspase-1 and this interaction correlates with the processing of pro-caspase-1 and the formation of the active caspase-1 p20. |
Source : | Sf9 Cells |
Species : | Human |
Tag : | GST |
Form : | Recombinant protein stored in 50mM Tris-HCl, pH 7.5, 150mM NaCl, 0.25mM DTT, 0.1mM EGTA, 0.1mM EDTA, 0.1mM PMSF, 25% glycerol. |
Bio-activity : | 20 nmol/min/mg |
Molecular Mass : | ~59 kDa |
Protein length : | 1-299 aa |
Purity : | >90% |
Applications : | Kinase Assay, Western Blot |
Storage : | Store at –70°C. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. Avoid freeze/thaw cycles. |
Concentration : | 0.1μg/μl |
Gene Name : | RIPK2 receptor-interacting serine-threonine kinase 2 [ Homo sapiens ] |
Official Symbol : | RIPK2 |
Synonyms : | RIPK2; receptor-interacting serine-threonine kinase 2; receptor-interacting serine/threonine-protein kinase 2; CARD3; CARDIAK; RICK; RIP2; RIP-2; CARD-carrying kinase; growth-inhibiting gene 30; tyrosine-protein kinase RIPK2; receptor interacting protein 2; receptor-interacting protein 2; RIP-like-interacting CLARP kinase; CARD-containing IL-1 beta ICE-kinase; CARD-containing interleukin-1 beta-converting enzyme-associated kinase; CARD-containing interleukin-1 beta-converting enzyme (ICE)-associated kinase; receptor-interacting protein (RIP)-like interacting caspase-like apoptosis regulatory protein (CLARP) kinase; CCK; GIG30; |
Gene ID : | 8767 |
mRNA Refseq : | NM_003821 |
Protein Refseq : | NP_003812 |
MIM : | 603455 |
UniProt ID : | O43353 |
Chromosome Location : | 8q21 |
Pathway : | Activated TLR4 signalling, organism-specific biosystem; Adaptive Immune System, organism-specific biosystem; Canonical NF-kappaB pathway, organism-specific biosystem; Cytokine Signaling in Immune system, organism-specific biosystem; Downstream TCR signaling, organism-specific biosystem; FAS pathway and Stress induction of HSP regulation, organism-specific biosystem; IL12-mediated signaling events, organism-specific biosystem; |
Function : | ATP binding; CARD domain binding; CARD domain binding; LIM domain binding; non-membrane spanning protein tyrosine kinase activity; nucleotide binding; protein binding; protein homodimerization activity; protein serine/threonine kinase activity; signal transducer activity; |
Products Types
◆ Recombinant Protein | ||
RIPK2-5565H | Recombinant Human RIPK2, GST-tagged | +Inquiry |
RIPK2-5564H | Recombinant Human RIPK2 Protein, His-tagged | +Inquiry |
RIPK2-7616M | Recombinant Mouse RIPK2 Protein, His (Fc)-Avi-tagged | +Inquiry |
Ripk2-5522M | Recombinant Mouse Ripk2 Protein, Myc/DDK-tagged | +Inquiry |
Ripk2-1796R | Recombinant Rat Ripk2 protein, His & T7-tagged | +Inquiry |
◆ Lysates | ||
RIPK2-2333HCL | Recombinant Human RIPK2 293 Cell Lysate | +Inquiry |
◆ Assay kits | ||
Kit-1623 | RIPK2 Kinase Binding Assay Kit | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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