Active Recombinant Human NRG1 protein(Ser2-Lys246), Fc-tagged
Cat.No. : | NRG1-7320H |
Product Overview : | Recombinant Human NRG1 isoform beta1 (Q02297-6)(Ser 2-Lys 246) was expressed in HEK293, fused with the Fc region of Mouse IgG1 at the N-terminus. |
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Source : | HEK293 |
Species : | Human |
Tag : | N-Fc |
Protein length : | Ser2-Lys246 |
Form : | Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization. |
Bio-activity : | 1. Measured by its ability to bind with human ErbB4-His in a functional ELISA. 2. Measured by its ability to bind with human ErbB3-His in a functional ELISA. |
Molecular Mass : | The recombinant human NRG1/mFc is a disulfide-linked homodimer. The reduced monomer comprises 481 amino acids and has a predicted molecular mass of 53.4 kDa. The apparent molecular mass of the monomer is approximately 67 kDa in SDS-PAGE under reducing conditions due to glycosylation. |
Endotoxin : | < 1.0 EU per μg of the protein as determined by the LAL method. |
Purity : | > 88 % as determined by SDS-PAGE |
Storage : | Samples are stable for up to twelve months from date of receipt at -20°C to -80°C. Store it under sterile conditions at -20°C to -80°C. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles. |
Reconstitution : | It is recommended that sterile water be added to the vial to prepare a stock solution of 0.2 ug/ul. Centrifuge the vial at 4°C before opening to recover the entire contents. |
Gene Name : | NRG1 neuregulin 1 [ Homo sapiens ] |
Official Symbol : | NRG1 |
Synonyms : | NRG1; neuregulin 1; HGL; pro-neuregulin-1, membrane-bound isoform; GGF; HRG; NDF; MSTP131; pro-NRG1; glial growth factor; neu differentiation factor; neuregulin 1 type IV beta 3; neuregulin 1 type IV beta 1a; sensory and motor neuron derived factor; heregulin, alpha (45kD, ERBB2 p185-activator); ARIA; GGF2; HRG1; HRGA; SMDF; MST131; |
Gene ID : | 3084 |
mRNA Refseq : | NM_001159995 |
Protein Refseq : | NP_001153467 |
MIM : | 142445 |
UniProt ID : | Q02297 |
Products Types
◆ Lysates | ||
NRG1-1592HCL | Recombinant Human NRG1 cell lysate | +Inquiry |
NRG1-836CCL | Recombinant Canine NRG1 cell lysate | +Inquiry |
NRG1-1591HCL | Recombinant Human NRG1 cell lysate | +Inquiry |
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For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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