"LTA" Related Products

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Mouse Anti-LTA Monoclonal Antibody

Cat.No.: DMABT-H19263
Product Overview: Mouse Anti-LTA Monoclonal Antibody
Antigen Description: Tumor necrosis factor-beta (TNF-beta), also known as lymphotoxin-alpha (LT-alpha) is a potent lymphoid factor that exerts cytotoxic effects on a wide range of tumor cells and certain other target cells. TNF-beta possesses a signal peptide sequence and is a secreted protein; however, TNF-beta is also present on the surface of activated T, B and LAK cells as a complex with LT-beta. Bioactive TNF-beta exists as a homotrimer.
Target: LTA
Immunogen: E.coli expressed, recombinant human TNF-beta
Host: Mouse
Isotype: IgG1, kappa
species: Human
Clone: 460-349-9
Conjugation: N/A
Applications: ELISA,ELISPOT,Neut
Preparation: The LEAF (Low Endotoxin, Azide-Free) antibody was Purified by affinity chromatography.
Usage recommendation: Each lot of this antibody is quality control tested by ELISA assay. For ELISA capture applications, a concentration range of 1-4 μg/ml is recommended. To obtain a linear standard curve, serial dilutions of TNF-beta recombinant protein ranging from 1000 to 8 pg/ml are recommended for each ELISA plate. It is recommended that the reagent be titrated for optimal performance for each application.
Concentration: 1.0 mg/ml
Storage: The antibody solution should be stored undiluted at 4 °C. This LEAF solution contains no preservative; handle under aseptic conditions.
Size: 500 μg
Gene Name: LTA lymphotoxin alpha (TNF superfamily, member 1) [ Homo sapiens ]
Official Symbol: LTA
Synonyms: LTA; lymphotoxin alpha (TNF superfamily, member 1); TNFB; lymphotoxin-alpha; LT; TNFSF1; LT-alpha; TNF-beta; tumor necrosis factor beta; tumor necrosis factor ligand superfamily member 1;
Gene ID: 4049
mRNA Refseq: NM_000595
Protein Refseq: NP_000586
MIM: 153440
UniProt ID: P01374
Chromosome Location: 6p21.3
Pathway: Apoptosis, organism-specific biosystem; Cytokine-cytokine receptor interaction, organism-specific biosystem; Cytokine-cytokine receptor interaction, conserved biosystem; HTLV-I infection, organism-specific biosystem; HTLV-I infection, conserved biosystem; Herpes simplex infection, organism-specific biosystem; Herpes simplex infection, conserved biosystem;
Function: cytokine activity; receptor binding; tumor necrosis factor receptor binding;

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Optional requirements on this protein    +Expand
C-fusion    N-fusion   Non-tagged
His    GST   Fc   Others
<1.0 eu/μg    <0.1 eu/μg   <0.01 eu/μg   Not required
Monomer Isolation    Dimer Isolation    Not required
>80% by SDS-PAGE    >90% by SDS-PAGE   >95% by SDS-PAGE   Others

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