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Mouse Anti-UBB Monoclonal Antibody

Cat.No.: DMABT-H18083
Product Overview: Mouse Anti-UBB Monoclonal Antibody
Antigen Description: Ubiquitin is a highly conserved polypeptide of 76 amino acid residues that is a widely distributed protein in eukaryotic cells. Recently several reports have shown that intracellular abnormal and short-lived proteins are degraded through the ubiquitin dependent proteolytic pathway in which the target protein is tagged with multi-ubiquitin molecules.
Target: UBB
Host: Mouse
Isotype: IgG1
species: Human
Clone: Gl3
Conjugation: N/A
Applications: IP
Storage: 4°C
Size: 400 μL
Ship: 4°C
Gene Name: UBB ubiquitin B [ Homo sapiens ]
Official Symbol: UBB
Synonyms: UBB; ubiquitin B; polyubiquitin-B; FLJ25987; MGC8385; polyubiquitin B; UBC; UBA52; RPS27A;
Gene ID: 7314
mRNA Refseq: NM_018955
Protein Refseq: NP_061828
MIM: 191339
UniProt ID: P0CG47
Chromosome Location: 17p12-p11.2
Pathway: APC/C-mediated degradation of cell cycle proteins, organism-specific biosystem; APC/C:Cdc20 mediated degradation of Cyclin B, organism-specific biosystem; APC/C:Cdc20 mediated degradation of Securin, organism-specific biosystem; APC/C:Cdc20 mediated degradation of mitotic proteins, organism-specific biosystem; APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1, organism-specific biosystem; Activated NOTCH1 Transmits Signal to the Nucleus, organism-specific biosystem; Activated NOTCH1 Transmits Signal to the Nucleus, organism-specific biosystem;
Function: protein binding; ubiquitin-protein ligase activity;

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Optional requirements on this protein    +Expand
C-fusion    N-fusion   Non-tagged
His    GST   Fc   Others
<1.0 eu/μg    <0.1 eu/μg   <0.01 eu/μg   Not required
Monomer Isolation    Dimer Isolation    Not required
>80% by SDS-PAGE    >90% by SDS-PAGE   >95% by SDS-PAGE   Others

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