Address: 45-1 Ramsey Road, Shirley, NY 11967, USA    USA: 1-631-559-9269  1-631-448-7888   Fax: 1-631-938-8127  Europe: 44-207-048-3343   Email: info@creative-biomart.com
Home > Products > Antibody > Monoclonal Antibodies > Rat Anti-Havcr1 Monoclonal Antibody

Rat Anti-Havcr1 Monoclonal Antibody

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By Species
Mouse(3)
By Source
Rat(3)
By Tag
N/A(2)
RPE(1)
Cat.No.:
DMAB36385
Product Overview:
Rat Anti-Havcr1 Monoclonal Antibody
Antigen Description:
Tim-1 is highly expressed by activated CD4+ T cells, and acts as a positive/negative co-stimulatory molecule of T cell proliferation, cytokine production and tolerance abrogation, and is the receptor for Tim-4, expressed on APCs. Tim-1 expression is greater on Th2 than Th1 cells, and studies have shown that interaction between Tim-1 on Th2 cells and Tim-4 on dendritic cells (DCs), enhances Th2 cell function, and have implicated Tim-1 as a critical player in the development of atopic disease, and in particular airway hypersensitivity.
specificity:
It specifically recognises mouse Tim-1 (T-cell immunoglobulin mucin 1), a cell surface glycoprotein and member of the immunoglobulin superfamily, which was first identified as the hepatitis A virus cellular receptor (HAVCR), and is highly expressed in the liver (isoform Tim-1a) and the kidneys (isoform Tim-1b).
Target:
Havcr1
Immunogen:
Full-length mouse Tim-1-Ig, containing both the IgV and mucin domains of Tim-1.
Host:
Rat
Isotype:
IgG2a
species:
Mouse
Clone:
SNU2-20
Purification:
Purified IgG
Conjugation:
RPE
Applications:
Flow Cyt
Dilution:
Flow Cytometry: Use 10ul of the suggested working dilution to label 1x106 cells in 100ul.
Preparation:
Purified IgG prepared by affinity chromatography on Protein G from tissue culture supernatant
Reconstitution:
Reconstitute with 1.0 ml distilled water. Care should be taken during reconstitution as the protein may appear as a film at the bottom of the vial.
Storage:
Prior to reconstitution store at +4°C. After reconstitution store at +4°C. DO NOT FREEZE. This product should be stored undiluted. This product is photosensitive and should be protected from light. Should this product contain a precipitate we recommend microcentrifugation before use.
Preservative:
0.09% Sodium Azide (NaN3),1% Bovine Serum Albumin,5% Sucrose
Shelf life:
12 months from date of reconstitution.
Size:
100 TESTS


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Optional requirements on this protein +Expand
C-fusion   N-fusion  Non-tagged
His   GST  Fc  Others
<1.0 eu/μg   <0.1 eu/μg  <0.01 eu/μg  Not required
Monomer Isolation   Dimer Isolation   Not required
>80% by SDS-PAGE   >90% by SDS-PAGE  >95% by SDS-PAGE  Others
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45-1 Ramsey Road, Shirley, NY 11967, USA
USA: 1-631-559-9269  1-631-448-7888
Europe: 44-207-048-3343
FAX: 1-631-938-8127
EMAIL: info@creative-biomart.com

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