Active Recombinant Mouse Vascular Endothelial Growth Factor A

• Cat.No.: Vegfa-582M
• Product Overview: Recombinant Mouse VEGF-120 is a truncated version of Mouse VEGF-165. Mouse VEGF-120 is a homodimer with a molecular weight of 28.2 kDa

Specification

• Cat. No.: Vegfa-582M
• Description: Vascular endothelial growth factor A (VEGF-A) is a protein that in humans is encoded by the VEGFA gene. This gene is a member of the platelet-derived growth factor (PDGF)/vascular endothelial growth factor (VEGF) family and encodes a protein that is often found as a disulfide linked homodimer. As its name implies, VEGF-A activity has been studied mostly on cells of the vascular endothelium, although it does have effects on a number of other cell types.
• Species: Mouse
• Source: E.coli
• Form: Lyophilized with no additives.
• Purity: Purity Greater than 97% as determined by: Reducing and non-reducing SDS-PAGE. Analytical HPLC.
• Bio-activity: In process
• Physical Appearance: Sterile Filtered white lyophilized (freeze-dried) powder.
• Solubility: It is recommended to reconstitute the lyophilized product with sterile water at a concentration of 0.1 ?C 0.5 mgμs/ml, which can be further diluted into other aqueous solutions.
• Purity Greater than 97% as determined by: Reducing and non-reducing SDS-PAGE. Analytical HPLC
• Protein Content determined by: UV spectroscopy at 280 nm. Quantitation on SDS-PAGE against a known standard.
• Endotoxin Level: Endotoxin level as measured by LAL is <0.01ng/ug or <0.1EU/ug.
• Amino acid sequence: APTTEGEQK SHEVIKFMDV YQRSYCRPIE TLVDIFQEYP DEIEYIFKPS CVPLMRCAGC CNDEALECVPTSESNITMQI MRIKPHQSQH IGEMSFLQHS RCECRPKKDR TKPEKCDKRPR R
• Storage: Lyophilized product is very stable at -20 degrees. Reconstituted material should be aliquoted and frozen at -20. It is recommended to add a carrier protein (0.1% HSA or BSA) for long term storage.

Gene Information

• Gene Name: Vegfa vascular endothelial growth factor A [ Mus musculus ]
• Official Symbol: Vegfa
• Synonyms: Vegfa; vascular endothelial growth factor A;Vpf; Vegf; Vegf-a; Vegf120; Vegf164; VEGF120; VPF; Vegf188; OTTMUSP00000017463; VEGF164; OTTMUSP00000017464; VEGF-A; OTTMUSP00000022243; vascular permeability factor; VEGF188; MGC70609; MVCD1; VEGF; Vascular permeability factor; vascular endothelial growth factor; vascular endothelial growth factor isoform VEGF165
• Gene ID: 22339
• mRNA Refseq: NM_001025250
• Protein Refseq: NP_001020421
• UniProt ID: Q00731
• Chromosome Location: 17 C; 17 24.2 cM
• Pathway: Bladder cancer; Focal adhesion; Cytokine-cytokine receptor interaction; Pancreatic cancer; Pathways in cancer; Renal cell carcinoma; VEGF signaling pathway; mTOR signaling pathway
• Function: growth factor activity; heparin binding