Recombinant Human ATAD2 full-length ORF ( AAH19909.1, 1 aa - 362 aa), fused with GST-tag at N-terminal, was expressed in Wheat germ.
A large family of ATPases has been described, whose key feature is that they share a conserved region of about 220 amino acids that contains an ATP-binding site. The proteins that belong to this family either contain one or two AAA (ATPases Associated with diverse cellular Activities) domains. AAA family proteins often perform chaperone-like functions that assist in the assembly, operation, or disassembly of protein complexes. The protein encoded by this gene contains two AAA domains, as well as a bromodomain.
50 mM Tris-HCI, 10 mM reduced Glutathione, pH8.0 in the elution buffer.
Store at -80°C. Aliquot to avoid repeated freezing and thawing.
PDB rendering basedon 1adx.