Active Native Human CPB2
Cat.No. : | CPB2-8517H |
Product Overview : | Native Human TAFI is prepared from fresh frozen human plasma by a modification of the method of Bajzar, et. al. |
- Specification
- Gene Information
- Related Products
Description : | Carboxypeptidases are enzymes that hydrolyze C-terminal peptide bonds. The carboxypeptidase family includes metallo-, serine, and cysteine carboxypeptidases. According to their substrate specificity, these enzymes are referred to as carboxypeptidase A (cleaving aliphatic residues) or carboxypeptidase B (cleaving basic amino residues). The protein encoded by this gene is activated by trypsin and acts on carboxypeptidase B substrates. After thrombin activation, the mature protein downregulates fibrinolysis. Polymorphisms have been described for this gene and its promoter region. |
Source : | Human |
Species : | Human |
Form : | 20 mM Hepes, 150 mM NaCl, pH 7.4 |
Bio-activity : | Hippuryl-L-Arginine hydrolysis. Activity is determined measuring the rate of hydrolysis of hipuryl-L- Arg following activation with the thrombin/ thrombomodulin complex. |
Molecular Mass : | 60,000 |
Purity : | >95% by SDS-PAGE |
Storage : | -80℃ |
Gene Name : | CPB2 carboxypeptidase B2 (plasma) [ Homo sapiens ] |
Official Symbol : | CPB2 |
Synonyms : | CPB2; carboxypeptidase B2 (plasma); carboxypeptidase B2 (plasma, carboxypeptidase U); carboxypeptidase B2; carboxypeptidase R; carboxypeptidase U; CPU; PCPB; plasma carboxypeptidase B; TAFI; thrombin activatable fibrinolysis inhibitor; carboxypeptidase B-like protein; thrombin-activable fibrinolysis inhibitor; thrombin-activatable fibrinolysis inhibitor; |
Gene ID : | 1361 |
mRNA Refseq : | NM_001872 |
Protein Refseq : | NP_001863 |
MIM : | 603101 |
UniProt ID : | Q96IY4 |
Chromosome Location : | 13q14.11 |
Pathway : | Complement and Coagulation Cascades, organism-specific biosystem; Complement and coagulation cascades, organism-specific biosystem; Complement and coagulation cascades, conserved biosystem; Pancreatic secretion, organism-specific biosystem; Pancreatic secretion, conserved biosystem; Protein digestion and absorption, organism-specific biosystem; Protein digestion and absorption, conserved biosystem; |
Function : | metal ion binding; metallocarboxypeptidase activity; metallopeptidase activity; peptidase activity; zinc ion binding; |
Products Types
◆ Recombinant Protein | ||
CPB2-1221R | Recombinant Rat CPB2 Protein, His (Fc)-Avi-tagged | +Inquiry |
Cpb2-2285M | Recombinant Mouse Cpb2 Protein, Myc/DDK-tagged | +Inquiry |
CPB2-3301H | Recombinant Human CPB2 Protein, MYC/DDK-tagged | +Inquiry |
CPB2-1778H | Recombinant Human CPB2 Protein, GST-tagged | +Inquiry |
CPB2-169H | Recombinant Human CPB2 Protein, MYC/DDK-tagged, C13 and N15-labeled | +Inquiry |
◆ Native Protein | ||
CPB2-27270TH | Native Human CPB2 | +Inquiry |
◆ Lysates | ||
CPB2-1710MCL | Recombinant Mouse CPB2 cell lysate | +Inquiry |
CPB2-2252HCL | Recombinant Human CPB2 cell lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
Inquiry
0
Inquiry Basket