Recombinant Human Prominin 1, GST-tagged
Cat.No. : |
PROM1-73H |
Product Overview : |
Recombinant Human PROM1 (693 a.a. - 790 a.a.) fused with GST-tag at N-terminal, was expressed in wheat germ. |
- Specification
- Gene Information
- Related Products
Cat. No. : |
PROM1-73H |
Description : |
This gene encodes a pentaspan transmembrane glycoprotein. The protein localizes to membrane protrusions and is often expressed on adult stem cells, where it is thought to function in maintaining stem cell properties by suppressing differentiation. Mutations in this gene have been shown to result in retinitis pigmentosa and Stargardt disease. Expression of this gene is also associated with several types of cancer. This gene is expressed from at least five alternative promoters that are expressed in a tissue-dependent manner. Multiple transcript variants encoding different isoforms have been found for this gene. |
Source : |
wheat germ |
Molecular Mass : |
36.52 kDa |
Sequence : |
STLYQSVKILQRTGNGLLERVTRIL ASLDFAQNFITNNTSSVIIEETKKY GRTIIGYFEHYLQWIEFSISEKVAS CKPVATALDTAVDVFLCSYIIDP |
Storagebuffer : |
50 mM Tris-HCI, 10 mM reduced Glutathione, pH 8.0 in the elution buffer. |
Applications : |
ELISA; WB |
Storage : |
Store at -80°C. Aliquot to avoid repeated freezing and thawing. |
OfficialSymbol : |
PROM1 |
Gene Name : |
PROM1 prominin 1 [Homo sapiens] |
Synonyms : |
prominin 1; prominin (mouse)-like 1; AC133; Stargardt disease 4 (autosomal dominant); CD133; OTTHUMP00000217744; RP41; OTTHUMP00000217745; PROML1; OTTHUMP00000217746; Antigen AC133; hProminin; Prominin-like protein 1; hematopoietic stem cell antigen; CORD12; prominin-1; MCDR2; prominin-like 1; STGD4; CD133 antigen; macular dystrophy, retinal 2; MSTP061 |
Gene ID : |
8842 |
mRNA Refseq : |
NM_006017 |
Protein Refseq : |
NP_006008 |
MIM : |
604365 |
UniProt ID : |
O43490 |
Chromosome Location : |
4p15.32 |
Function : |
actinin binding; cadherin binding; protein binding |
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.