Recombinant Human CP, GST-tagged

• Cat.No.: CP-11507H
• Product Overview: Recombinant Human CP protein, fused to GST-tag, was expressed in E.coli and purified by GSH-sepharose.

Specification

• Description: The protein encoded by this gene is a metalloprotein that binds most of the copper in plasma and is involved in the peroxidation of Fe(II)transferrin to Fe(III) transferrin. Mutations in this gene cause aceruloplasminemia, which results in iron accumulation and tissue damage, and is associated with diabetes and neurologic abnormalities. Two transcript variants, one protein-coding and the other not protein-coding, have been found for this gene.
• Source: E.coli
• Species: Human
• Tag: GST
• Protein length: 194-446a.a.
• Storage: The protein is stored in PBS buffer at -20℃. Avoid repeated freezing and thawing cycles.
• Storage Buffer: 1M PBS (58mM Na2HPO4,17mM NaH2PO4, 68mM NaCl, pH8. ) added with 100mM GSH and 1% Triton X-100,15%glycerol.

Gene Information

• Gene Name: CP ceruloplasmin (ferroxidase) [ Homo sapiens ]
• Official Symbol: CP
• Synonyms: CP; ceruloplasmin (ferroxidase); ceruloplasmin; CP-2
• Gene ID: 1356
• mRNA Refseq: NM_000096
• Protein Refseq: NP_000087
• MIM: 117700
• UniProt ID: P00450
• Chromosome Location: 3q23-q25
• Pathway: HIF-1-alpha transcription factor network, organism-specific biosystem; Iron uptake and transport, organism-specific biosystem; Metal ion SLC transporters, organism-specific biosystem; Porphyrin and chlorophyll metabolism, organism-specific biosystem; Porphyrin and chlorophyll metabolism, conserved biosystem; SLC-mediated transmembrane transport, organism-specific biosystem; Transmembrane transport of small molecules, organism-specific biosystem
• Function: chaperone binding; copper ion binding; ferroxidase activity; metal ion binding; oxidoreductase activity