Recombinant Human EIF2B3, GST-tagged
Cat.No. : | EIF2B3-12355H |
Product Overview : | Recombinant Human EIF2B3 protein, fused to GST-tag, was expressed in E.coli and purified by GSH-sepharose. |
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Description : | The protein encoded by this gene is one of the subunits of initiation factor eIF2B, which catalyzes the exchange of eukaryotic initiation factor 2-bound GDP for GTP. It has also been found to function as a cofactor of hepatitis C virus internal ribosome entry site-mediated translation. Mutations in this gene have been associated with leukodystrophy with vanishing white matter. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. |
Source : | E.coli |
Species : | Human |
Tag : | GST |
Protein length : | C-term-218a.a. |
Storage : | The protein is stored in PBS buffer at -20℃. Avoid repeated freezing and thawing cycles. |
Storage Buffer : | 1M PBS (58mM Na2HPO4,17mM NaH2PO4, 68mM NaCl, pH8. ) added with 100mM GSH and 1% Triton X-100,15%glycerol. |
Gene Name : | EIF2B3 eukaryotic translation initiation factor 2B, subunit 3 gamma, 58kDa [ Homo sapiens ] |
Official Symbol : | EIF2B3 |
Synonyms : | EIF2B3; eukaryotic translation initiation factor 2B, subunit 3 gamma, 58kDa; eukaryotic translation initiation factor 2B, subunit 3 (gamma, 58kD); translation initiation factor eIF-2B subunit gamma; EIF 2B; EIF2Bgamma; eIF-2B GDP-GTP exchange factor subunit gamma; EIF-2B; |
Gene ID : | 8891 |
mRNA Refseq : | NM_001166588 |
Protein Refseq : | NP_001160060 |
MIM : | 606273 |
UniProt ID : | Q9NR50 |
Chromosome Location : | 1p34.1 |
Pathway : | Cap-dependent Translation Initiation, organism-specific biosystem; Eukaryotic Translation Initiation, organism-specific biosystem; Gene Expression, organism-specific biosystem; Metabolism of proteins, organism-specific biosystem; RNA transport, organism-specific biosystem; RNA transport, conserved biosystem; Recycling of eIF2:GDP, organism-specific biosystem; |
Function : | contributes_to guanyl-nucleotide exchange factor activity; contributes_to guanyl-nucleotide exchange factor activity; nucleotidyltransferase activity; protein binding; contributes_to translation factor activity, nucleic acid binding; contributes_to transl |
Products Types
◆ Recombinant Protein | ||
EIF2B3-3157H | Recombinant Human EIF2B3 Protein, GST-tagged | +Inquiry |
Eif2b3-357M | Recombinant Mouse Eif2b3 Protein, MYC/DDK-tagged | +Inquiry |
EIF2B3-1240R | Recombinant Rhesus Macaque EIF2B3 Protein, His (Fc)-Avi-tagged | +Inquiry |
EIF2B3-333H | Recombinant Human EIF2B3 Protein, His-tagged | +Inquiry |
EIF2B3-327H | Recombinant Human EIF2B3 Protein, MYC/DDK-tagged | +Inquiry |
◆ Lysates | ||
EIF2B3-6671HCL | Recombinant Human EIF2B3 293 Cell Lysate | +Inquiry |
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For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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