Recombinant Human FAAH, GST-tagged

• Cat.No.: FAAH-12629H
• Product Overview: Recombinant Human FAAH protein, fused to GST-tag, was expressed in E.coli and purified by GSH-sepharose.

Specification

• Description: This gene encodes a protein that is responsible for the hydrolysis of a number of primary and secondary fatty acid amides, including the neuromodulatory compounds anandamide and oleamide.
• Source: E.coli
• Species: Human
• Tag: GST
• Protein length: 236-579a.a.
• Storage: The protein is stored in PBS buffer at -20℃. Avoid repeated freezing and thawing cycles.
• Storage Buffer: 1M PBS (58mM Na2HPO4,17mM NaH2PO4, 68mM NaCl, pH8. ) added with 100mM GSH and 1% Triton X-100,15%glycerol.

Gene Information

• Gene Name: FAAH fatty acid amide hydrolase [ Homo sapiens ]
• Official Symbol: FAAH
• Synonyms: FAAH; fatty acid amide hydrolase; fatty-acid amide hydrolase 1; FAAH 1; oleamide hydrolase 1; anandamide amidohydrolase 1; FAAH-1; MGC102823; MGC138146
• Gene ID: 2166
• mRNA Refseq: NM_001441
• Protein Refseq: NP_001432
• UniProt ID: O00519
• Chromosome Location: 1p35-p34
• Pathway: Retrograde endocannabinoid signaling, organism-specific biosystem; Retrograde endocannabinoid signaling, conserved biosystem; anandamide degradation, organism-specific biosystem; anandamide degradation, conserved biosystem
• Function: acylglycerol lipase activity; amidase activity; carbon-nitrogen ligase activity, with glutamine as amido-N-donor; fatty acid amide hydrolase activity; hydrolase activity, acting on ester bonds; phospholipid binding; protein homodimerization activity

Reviews

08/18/2022

Critical expertise in protein engineering, unmatched in quality and efficiency.

04/03/2021

Dependable peptide synthesis, accelerates our peptide-focused projects effectively.

08/28/2019

Efficient protein purification, delivers consistent yields and purity.

Q&As

How does FAAH contribute to the metabolism of bioactive lipids and their physiological effects?

FAAH is involved in the metabolism of bioactive lipids, affecting various physiological functions.

How does FAAH (Fatty Acid Amide Hydrolase) regulate the breakdown of endocannabinoids and fatty acid amides?

FAAH breaks down endocannabinoids and fatty acid amides, regulating their levels and effects in the body.

How does FAAH influence mood and behaviors, particularly in relation to anxiety and depression?

FAAH influences mood and behavior, playing a role in conditions like anxiety and depression.

What are the mechanisms by which FAAH modulates the endocannabinoid system and its related signaling pathways?

FAAH regulates the endocannabinoid system, affecting neurotransmission and cellular signaling.

What is the impact of FAAH on appetite regulation and energy balance?

FAAH impacts appetite and energy balance, potentially influencing eating behaviors and metabolic processes.

How do alterations in FAAH activity or expression affect the development and treatment of substance abuse disorders?

Changes in FAAH activity can influence substance abuse disorders, impacting addiction and treatment responses.

What role does FAAH play in modulating pain perception and the body's response to stress?

FAAH modulates pain and stress responses by controlling endocannabinoid signaling.