Recombinant Cynomolgus IFNAR1, Fc tagged

• Cat.No.: IFNAR1-78C
• Product Overview: Recombinant Cynomolgus IFNAR1 (NP_001253442.1) (Met1-Lys437), fused with the Fc region of human IgG1 at the C-terminus, was produced in Human Cells.

Specification

• Source: Human Cells
• Species: Cynomolgus
• Tag: Fc
• Predicted N Terminal: Ala 25
• Form: Lyophilized from sterile PBS, pH 7.4.Normally 5 % - 8 % trehalose and mannitol are added as protectants before lyophilization.
• Molecular Mass: The recombinant cynomolgus IFNAR1 is a disulfide-linked homodimer. The reduced monomer comprises 654 amino acids and has a calculated molecular mass of 74.5 KDa.The apparent molecular mass of the protein is approximately 92-120 KDa in SDS-PAGE.
• Endotoxin: < 1.0 eu per μg of the protein as determined by the LAL method.
• Purity: >95 % as determined by SDS-PAGE
• Stability: Samples are stable for up to twelve months from date of receipt at -70oC.
• Storage: Store it under sterile conditions at -20oC~-70oC. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
• Reconstitution: It is recommended that sterile water be added to the vial to prepare a stock solution. Centrifuge the vial at 4℃ before opening to recover the entire contents.

Reviews

12/09/2021

An additional advantage of selecting the IFNAR1 protein is the outstanding technical support offered by its manufacturer.

06/05/2020

The combination of the protein's excellence and the manufacturer's exceptional technical support equips me with the necessary resources to overcome experimental obstacles and achieve groundbreaking results.

09/30/2016

Their unwavering commitment to customer satisfaction assures me that any challenges or queries I may encounter will be expertly resolved.

Q&As

How is IFNAR1 protein targeted in the treatment of autoimmune diseases?

In the treatment of autoimmune diseases, IFNAR1 protein can be targeted to modulate the immune response and reduce inflammation.

How is IFNAR1 protein used in research settings?

In research settings, IFNAR1 protein is often studied to better understand its role in immune signaling pathways and disease processes.

How is IFNAR1 protein clinically relevant?

IFNAR1 protein is clinically relevant in the treatment of diseases such as viral infections, autoimmune diseases, and certain cancers.

Are there any specific drugs that target IFNAR1 protein?

Yes, there are drugs that specifically target IFNAR1 protein, including some that are used in the treatment of multiple sclerosis and certain viral infections.

What are the potential applications of IFNAR1 protein in cancer treatment?

IFNAR1 protein may be targeted to enhance the body's immune response against cancer cells, leading to potential immunotherapy applications.