Active Recombinant Mouse Cd14 Protein, Fc-tagged
Cat.No. : | Cd14-117M |
Product Overview : | Recombinant mouse Cd14 (Ala18Pro345) protein with Fc region of human IgG1 at the C-terminus was expressed in mouse myeloma cell line, NS0. |
- Specification
- Gene Information
- Related Products
Description : | This gene encodes a protein that plays an important role in the innate immune response and is expressed in monocyte/macrophage cells. This gene product acts as a co-receptor that binds several microbial and fungal molecules, including lipopolysaccharides (LPS). This proteins LPS-binding activity is enhanced by the LPS binding protein (LBP) to allow binding to the TLR4-MD-2 co-receptor complex. The product of this gene is found in two forms, either as a soluble protein or attached to the cell surface by a glycosylphosphatidylinositol anchor. |
Source : | Mammalian cells |
Species : | Mouse |
Tag : | Fc |
Bio-activity : | Measured by its ability to enhance LPS-induced IL-6 secretion by mouse splenocytes. The ED50 for this effect is 0.4-2.4 µg/mL. |
Molecular Mass : | Predicted Molecular Mass: 61.8 kDa (monomer) SDS-PAGE: 85-95 kDa, reducing conditions |
N-terminal Sequence Analysis : | Ala18 |
Endotoxin : | <0.01 EU per 1 μg of the protein by the LAL method. |
Purity : | >95%, by SDS-PAGE under reducing conditions and visualized by silver stain |
Storage : | Avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 centigrade as supplied. 1 month, 2 to 8 centigrade under sterile conditions after reconstitution. 3 months, -20 to -70 centigrade under sterile conditions after reconstitution. |
Storage Buffer : | Lyophilized from a 0.2 μm filtered solution in PBS. |
Reconstitution : | Reconstitute at 1 mg/mL in sterile PBS. |
Gene Name : | Cd14 |
Official Symbol : | Cd14 CD14 antigen [ Mus musculus (house mouse) ] |
Synonyms : | Cd14; CD14 antigen; monocyte differentiation antigen CD14; myeloid cell-specific leucine-rich glycoprotein |
Gene ID : | 12475 |
mRNA Refseq : | NM_009841 |
Protein Refseq : | NP_033971 |
UniProt ID : | P10810 |
Products Types
◆ Recombinant Protein | ||
Cd14-7M | Recombinant Mouse Cd14 Protein, His (Fc)-Avi-tagged | +Inquiry |
CD14-650H | Recombinant Human CD14 Protein, His-tagged | +Inquiry |
Cd14-648M | Recombinant Mouse Cd14 Protein, His-tagged | +Inquiry |
CD14-652H | Recombinant Human CD14 Protein, His-tagged | +Inquiry |
CD14-651H | Recombinant Human CD14 Protein, His-tagged | +Inquiry |
◆ Lysates | ||
CD14-1469RCL | Recombinant Rat CD14 cell lysate | +Inquiry |
CD14-2581MCL | Recombinant Mouse CD14 cell lysate | +Inquiry |
CD14-1604HCL | Recombinant Human CD14 cell lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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