Recombinant Human TYK2, His-tagged
Cat.No. : | TYK2-3508H |
Product Overview : | Recombinant Human TYK2 protein, fused to His-tag, was expressed in E.coli and purified by Ni-sepharose. |
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Source : | E.coli |
Species : | Human |
Tag : | His |
Protein length : | 901-1187aa |
Storage : | The protein is stored in PBS buffer at -20℃. Avoid repeated freezing and thawing cycles. |
Storage Buffer : | 1M PBS (58mM Na2HPO4,17mM NaH2PO4, 68mM NaCl, pH8. ) added with 300mM Imidazole and 0.7% Sarcosyl, 15%glycerol. |
Gene Name : | TYK2 tyrosine kinase 2 [ Homo sapiens ] |
Official Symbol : | TYK2 |
Synonyms : | TYK2; tyrosine kinase 2; non-receptor tyrosine-protein kinase TYK2; JTK1; |
Gene ID : | 7297 |
mRNA Refseq : | NM_003331 |
Protein Refseq : | NP_003322 |
MIM : | 176941 |
UniProt ID : | P29597 |
Chromosome Location : | 19p13.2 |
Pathway : | Cytokine Signaling in Immune system, organism-specific biosystem; Hepatitis C, organism-specific biosystem; Hepatitis C, conserved biosystem; Herpes simplex infection, organism-specific biosystem; Herpes simplex infection, conserved biosystem; IL-3 Signal |
Function : | ATP binding; growth hormone receptor binding; non-membrane spanning protein tyrosine kinase activity; nucleotide binding; protein tyrosine kinase activity; |
Products Types
◆ Recombinant Protein | ||
TYK2-03H | Recombinant Human TYK2 Protein, Myc/DDK-tagged | +Inquiry |
TYK2-01H | Recombinant Human TYK2 (JH2 domain, 575-869), N-FLAG-tagged | +Inquiry |
TYK2-02H | Recombinant Human TYK2 Protein (556-1187), N-DYKDDDDK-tagged | +Inquiry |
Tyk2-7543M | Recombinant Mouse Tyk2 protein(884-1174aa), His&Myc-tagged | +Inquiry |
TYK2-2284H | Recombinant Human TYK2 Protein, His (Fc)-Avi-tagged | +Inquiry |
◆ Lysates | ||
TYK2-1867HCL | Recombinant Human TYK2 cell lysate | +Inquiry |
◆ Assay kits | ||
Kit-1635 | TYK2 Activity Assay Kit | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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Q&As (5)
Ask a questionYes, TYK2 inhibitors might have potential in treating certain cancers and possibly other inflammatory conditions beyond autoimmune diseases.
TYK2 inhibition can potentially reduce inflammation and modulate immune responses without suppressing the entire immune system, unlike some other treatments.
Yes, there are several clinical trials evaluating the efficacy and safety of TYK2 inhibitors in various autoimmune diseases.
TYK2 inhibitors are more targeted, aiming to interfere with specific signaling pathways involved in the immune response compared to broad immunosuppressants.
Depending on the formulation, TYK2 inhibitors can be administered orally or through injections.
Customer Reviews (3)
Write a reviewTheir expertise in protein production and purification ensures the delivery of a high-quality product that consistently performs well in my experiments.
They are readily available to address any concerns or questions and supply valuable resources to assist in experimental design and optimization.
Should I encounter any challenges or require technical assistance, the manufacturer provides prompt and knowledgeable support.
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