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Active Recombinant Mouse Vtcn1, Fc-tagged

Cat.No. : Vtcn1-12M
Product Overview : Recombinant Mouse Vtcn1 (aa 29-258) is fused to the N-terminus of the Fc region of mouse IgG2a.
  • Specification
  • Gene Information
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Description : V-set domain-containing T-cell activation inhibitor 1 is a protein that in humans is encoded by the VTCN1 gene. B7H4 belongs to the B7 family (see CD80; MIM 112203) of costimulatory proteins. These proteins are expressed on the surface of antigen-presenting cells and interact with ligands (e.g., CD28; MIM 186760) on T lymphocytes.
Source : CHO cells
Species : Mouse
Tag : Fc
Form : Lyophilized from 0.2μm-filtered solution in PBS.
Bio-activity : Measured by its ablility to inhibit anti-CD3-induced proliferation of stimulated mouse T cells.
Endotoxin : <0.06EU/μg protein (LAL test; Lonza).
Purity : ≥98% (SDS-PAGE)
Stability : Stable for at least 1 year after receipt when stored at -20°C. Working aliquots are stable for up to 3 months when stored at -20°C.
Storage : Short Term Storage: +4°CLong Term Storage: -20°CHandling Advice: Avoid freeze/thaw cycles.
Reconstitution : Reconstitute at 100μg/ml in sterile PBS.
Gene Name : Vtcn1 V-set domain containing T cell activation inhibitor 1 [ Mus musculus (house mouse) ]
Official Symbol : Vtcn1
Synonyms : Vtcn1; B7x; B7h4; B7s1; BC032925; V-set domain containing T cell activation inhibitor 1; V-set domain containing T-cell activation inhibitor 1; t cell costimulatory molecule B7x; immune costimulatory protein B7-H4
Gene ID : 242122
mRNA Refseq : NM_178594
Protein Refseq : NP_848709
UniProt ID : Q7TSP5
Chromosome Location : 3 F2.2; 3
Pathway : Cell adhesion molecules (CAMs)
Function : receptor binding

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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