Recombinant Human TRIB2, GST-tagged
Cat.No. : | TRIB2-24H |
Product Overview : | Recombinant full-length human TRIB2 was expressed by baculovirus in Sf9 insect cells using an N-terminal GST tag. |
- Specification
- Gene Information
- Related Products
Description : | TRIB2 or tribbles homolog 2 proteins encode one of three members of the Tribbles family that share a Trb domain, which is homologous to protein serine-threonine kinases, but lacks the active site lysine and probably lacks a catalytic function. TRIB2 protein interacts and modulates the activity of signal transduction pathways in a number of physiological and pathological processes. TRIB2 is regulated by inflammatory stimuli in myeloid (THP-1) cells. TRIB2 can act as an oncogene that inactivates the transcription factor C/EBPalpha (CCAAT/enhancer-binding protein alpha) and causes acute myelogenous leukemia. TRIB2 is a p65-interacting negative regulator of NF-kappa-B-dependent transcription. |
Source : | Sf9 insect cells using baculovirus |
Species : | Human |
Tag : | GST |
Form : | 50mM Tris-HCl, pH 7.5, 150mM NaCl, 10mM glutathione, 0.1mM EDTA, 0.25mM DTT, 0.1mM PMSF, 25% glycerol. |
Molecular Mass : | ~64 kDa |
Applications : | Western Blot |
Storage : | Store product at –70oC. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. For most favorable performance, avoid repeated handling and multiple freeze/thaw cycles. |
Gene Name : | TRIB2 tribbles homolog 2 (Drosophila) [ Homo sapiens ] |
Official Symbol : | TRIB2 |
Synonyms : | TRIB2; tribbles homolog 2 (Drosophila); tribbles homolog 2; GS3955; TRB2; C5FW; FLJ57420; |
Gene ID : | 28951 |
mRNA Refseq : | NM_021643 |
Protein Refseq : | NP_067675 |
MIM : | 609462 |
UniProt ID : | Q92519 |
Chromosome Location : | 2p25.1 |
Function : | ATP binding; NOT nucleotide binding; NOT protein kinase activity; protein kinase inhibitor activity; transcription factor binding; transferase activity, transferring phosphorus-containing groups; ubiquitin protein ligase binding; ubiquitin-protein ligase regulator activity; |
Products Types
◆ Recombinant Protein | ||
TRIB2-0573H | Recombinant Human TRIB2 Protein (N2-N343), Tag Free | +Inquiry |
Trib2-6641M | Recombinant Mouse Trib2 Protein, Myc/DDK-tagged | +Inquiry |
TRIB2-2251H | Recombinant Human TRIB2 Protein, His (Fc)-Avi-tagged | +Inquiry |
TRIB2-326H | Recombinant Human TRIB2 Protein, His-tagged | +Inquiry |
TRIB2-9589M | Recombinant Mouse TRIB2 Protein, His (Fc)-Avi-tagged | +Inquiry |
◆ Lysates | ||
TRIB2-635HCL | Recombinant Human TRIB2 cell lysate | +Inquiry |
TRIB2-645HCL | Recombinant Human TRIB2 cell lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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