Recombinant Human killer cell lectin-like receptor subfamily K, member 1, His-tagged
Cat.No. : | KLRK1-379H |
Product Overview : | KLRK1, 73-216 aa, Human, His tag, E.coli |
- Specification
- Gene Information
- Related Products
Description : | KLRK1 is an activating receptor that has recently generated considerable interest. The most intriguing of these are a pair of closely related proteins called MICA and MICB. These are cell-surface molecules distantly related to MHC class I proteins, and the genes possess elements of heat shock promoters. MICA and MICB, therefore, are expressed during cell stress and are up-regulated in tumor cells and during viral infections. This receptor-ligand combination may play a critical role in the immune response to a variety of pathologies. Recombinant human KLRK1 protein, fused to His-tag at N-terminus, was expressed in E.coli. |
Source : | E.coli |
Species : | Human |
Tag : | His-tag |
Form : | Liquid. 20mM Tris-HCl buffer (pH8.0) containing 10% glycerol 0.4M Urea |
Molecular Mass : | 19.2 kDa(168aa) |
AA Sequence : | MGSSHHHHHH SSGLVPRGSH MGSMIWSAVF LNSLFNQEVQ IPLTESYCGP CPKNWICYKN NCYQFFDESK NWYESQASCM SQNASLLKVY SKEDQDLLKL VKSYHWMGLV HIPTNGSWQW EDGSILSPNL LTIIEMQKGD CALYASSFKG YIENCSTPNT YICMQRTV |
Purity : | >90% by SDS - PAGE |
Storage : | Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -20C or -70C. Avoid repeated freezing and thawing cycles. |
Concentration : | 0.5 mg/ml (determined by Bradford assay) |
Gene Name : | KLRK1 killer cell lectin-like receptor subfamily K, member 1 [ Homo sapiens ] |
Official Symbol : | KLRK1 |
Synonyms : | KLRK1; killer cell lectin-like receptor subfamily K, member 1; D12S2489E, DNA segment on chromosome 12 (unique) 2489 expressed sequence; NKG2-D type II integral membrane protein; CD314; KLR; NKG2 D; NKG2D; NK cell receptor D; NKG2-D-activating NK receptor; NKG2-D; D12S2489E; FLJ17759; FLJ75772; |
Gene ID : | 22914 |
mRNA Refseq : | NM_007360 |
Protein Refseq : | NP_031386 |
MIM : | 611817 |
UniProt ID : | P26718 |
Chromosome Location : | 12p13.2-p12.3 |
Pathway : | Adaptive Immune System, organism-specific biosystem; Immune System, organism-specific biosystem; Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell, organism-specific biosystem; Malaria, organism-specific biosystem; Malaria, conserved biosystem; Natural killer cell mediated cytotoxicity, organism-specific biosystem; Natural killer cell mediated cytotoxicity, conserved biosystem; |
Products Types
◆ Recombinant Protein | ||
KLRK1-036H | Recombinant Human KLRK1 Protein, C-His-tagged | +Inquiry |
KLRK1-392C | Recombinant Cynomolgus Monkey KLRK1 Protein, His (Fc)-Avi-tagged | +Inquiry |
KLRK1-4889M | Recombinant Mouse KLRK1 Protein, His (Fc)-Avi-tagged | +Inquiry |
KLRK1-215H | Recombinant Human KLRK1 Protein, hIgG-His-tagged | +Inquiry |
KLRK1-4905H | Recombinant Human KLRK1 Protein, GST-tagged | +Inquiry |
◆ Lysates | ||
KLRK1-001CCL | Recombinant Cynomolgus KLRK1 cell lysate | +Inquiry |
KLRK1-001HCL | Recombinant Human KLRK1 cell lysate | +Inquiry |
KLRK1-002HCL | Recombinant Human KLRK1 cell lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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