Recombinant Human ubiquitin-conjugating enzyme E2D 1, His-tagged
Cat.No. : | UBE2D1-695H |
Product Overview : | UBE2D1, 1-147aa, Human, His tag, E.coli |
- Specification
- Gene Information
- Related Products
Description : | UBE2D1 belongs to the ubiquitin-conjugating enzyme family. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes, or E1s, ubiquitin-conjugating enzymes, or E2s, and ubiquitin-protein ligases, or E3s. This gene encodes a member of the E2 ubiquitin-conjugating enzyme family. UBE2D1 is closely related to a stimulator of iron transport (SFT), and is up-regulated in hereditary hemochromatosis. It also functions in the ubiquitination of the tumor-suppressor protein p53 and the hypoxia-inducible transcription factor HIF1alpha by interacting with the E1 ubiquitin-activating enzyme and the E3 ubiquitin-protein ligases. Recombinant human UBE2D1 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography. |
Source : | E.coli |
Species : | Human |
Tag : | His-tag |
Form : | Liquid. In 20mM Tris-HCl buffer (pH8.0) containing 40% glycerol, 0.1M NaCl |
Molecular Mass : | 19.0 kDa (170aa), confirmed by MALDI-TOF |
AA Sequence : | MGSSHHHHHH SSGLVPRGSH MGSMALKRIQ KELSDLQRDP PAHCSAGPVG DDLFHWQATI MGPPDSAYQG GVFFLTVHFP TDYPFKPPKI AFTTKIYHPN INSNGSICLD ILRSQWSPAL TVSKVLLSIC SLLCDPNPDD PLVPDIAQIY KSDKEKYNRH AREWTQKYAM |
Purity : | >95% by SDS - PAGE |
Storage : | Can be stored at +4°C short term (1-2 weeks). For long term storage, aliquot and store at -20°C or -70°C. Avoid repeated freezing and thawing cycles. |
Concentration : | 1mg/ml (determined by Bradford assay) |
Gene Name : | UBE2D1 ubiquitin-conjugating enzyme E2D 1 [ Homo sapiens ] |
Official Symbol : | UBE2D1 |
Synonyms : | UBE2D1; ubiquitin-conjugating enzyme E2D 1; SFT, stimulator of Fe transport , ubiquitin conjugating enzyme E2D 1 (UBC4/5 homolog, yeast); ubiquitin-conjugating enzyme E2 D1; E2(17)KB1; UBC4/5; UBCH5; UbcH5A; UBC4/5 homolog; stimulator of Fe transport; ubiquitin-protein ligase D1; ubiquitin carrier protein D1; ubiquitin-conjugating enzyme E2(17)KB 1; ubiquitin-conjugating enzyme E2-17 kDa 1; ubiquitin-conjugating enzyme E2D 1 (UBC4/5 homolog, yeast); SFT; UBCH5A; |
Gene ID : | 7321 |
mRNA Refseq : | NM_001204880 |
Protein Refseq : | NP_001191809 |
MIM : | 602961 |
UniProt ID : | P51668 |
Chromosome Location : | 10q21.1 |
Pathway : | APC/C-mediated degradation of cell cycle proteins, organism-specific biosystem; APC/C:Cdc20 mediated degradation of Cyclin B, organism-specific biosystem; APC/C:Cdc20 mediated degradation of Securin, organism-specific biosystem; APC/C:Cdc20 mediated degradation of mitotic proteins, organism-specific biosystem; APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1, organism-specific biosystem; Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins, organism-specific biosystem; Adaptive Immune System, organism-specific biosystem; |
Function : | ATP binding; acid-amino acid ligase activity; ligase activity; nucleotide binding; protein binding; ubiquitin-protein ligase activity; |
Products Types
◆ Recombinant Protein | ||
UBE2D1-0040H | Recombinant Human UBE2D1 Protein (A2-M147), Tag Free | +Inquiry |
UBE2D1-0041H | Recombinant Human UBE2D1 Protein (A2-M147), His/Strep tagged | +Inquiry |
UBE2D1-4868R | Recombinant Rhesus Macaque UBE2D1 Protein, His (Fc)-Avi-tagged | +Inquiry |
UBE2D1-6051R | Recombinant Rat UBE2D1 Protein, His (Fc)-Avi-tagged | +Inquiry |
Ube2d1-6782M | Recombinant Mouse Ube2d1 Protein, Myc/DDK-tagged | +Inquiry |
◆ Lysates | ||
UBE2D1-589HCL | Recombinant Human UBE2D1 293 Cell Lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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