Recombinant Human ANTXRL, His-tagged

• Cat.No.: ANTXRL-3506H
• Product Overview: Anthrax toxin receptor-like (ANTXRL)

Specification

• Source: E. Coli or Yeast
• Species: Human
• Tag: His
• Form: This item requires custom production and lead time is between 5-9 weeks. We can custom produce according to your specifications.
• Protein length: 565
• Purity: >90%
• Notes: Small volumes of ANTXRL recombinant protein may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice.
• Storage: Store at -20 degree C. For extended storage, store at -20 or -80 degree C.
• Storage Buffer: PBS pH 7.4, 50% glycerol
• Warning: This product is for research use only. Not for use in diagnostic or therapeutic procedures.

Gene Information

• Gene Name: ANTXRL anthrax toxin receptor-like [ Homo sapiens ]
• Official Symbol: ANTXRL
• Synonyms: ANTXRL; anthrax toxin receptor-like
• Gene ID: 195977
• mRNA Refseq: NM_001278688
• Protein Refseq: NP_001265617
• UniProt ID: A6NF34
• Chromosome Location: 10q11.22
• Function: metal ion binding; receptor activity

Reviews

06/06/2022

ANTXRL is extensively used in protein electron microscopy structure analysis due to its compatibility with this technique, providing crucial insights into molecular architectures.

01/24/2022

Researchers can rely on ANTXRL to deliver reliable and accurate results in ELISA experiments, ensuring precise measurement and quantification of target proteins.

08/13/2019

Its versatility and reliability make ANTXRL an excellent option for researchers seeking top-notch performance in ELISA and protein electron microscopy structure analysis.

03/08/2019

Its exceptional sensitivity and specificity make it an ideal choice for quantitative protein detection and analysis.

Q&As

Are there any known ligands or binding partners of ANTXRL?

The specific ligands or binding partners of ANTXRL have not been extensively studied. However, as ANTXRL shares structural similarity with ANTXR2, it is possible that they may interact with similar proteins or have common binding partners. Further research is necessary to identify the specific ligands or binding partners of ANTXRL.

Are there any known genetic mutations or variants associated with the ANTXRL gene?

Currently, there is limited information available regarding specific genetic mutations or variants in the ANTXRL gene. Further research is needed to identify potential variations in the gene and their implications.

Is there any research suggesting a potential role of ANTXRL protein in cancer?

Currently, there is limited research on the potential role of ANTXRL protein in cancer. However, some studies have shown altered expression of ANTXRL protein in certain types of cancer, indicating a possible association. Further investigations are required to elucidate the potential contribution of ANTXRL protein to cancer development and progression.

Does ANTXRL protein interact with other proteins?

The ANTXRL protein may interact with other proteins to exert its functional roles. However, the specific protein-protein interactions involving ANTXRL protein have not been extensively studied and documented. Future research may uncover its binding partners and shed light on its molecular interactions.

Are there any animal models or knockout studies for studying the ANTXRL protein?

Currently, there are no well-established animal models specifically targeting the ANTXRL protein. However, knockout studies could be performed in model organisms to investigate the effects of ANTXRL protein loss on cellular processes or animal phenotypes.

Are there any known signaling pathways or molecular mechanisms associated with the ANTXRL protein?

The signaling pathways and molecular mechanisms associated with the ANTXRL protein are not extensively characterized. However, it is likely involved in intracellular signaling cascades through its interactions with other proteins and involvement in endocytic processes. Further studies are required to uncover specific signaling pathways associated with the ANTXRL protein.

Is the ANTXRL protein conserved across different species?

The ANTXRL protein is relatively conserved across different species, including mammals. While there may be variations in the protein sequence, the overall structure and functional domains are conserved, indicating its importance in cellular processes.

Has the ANTXRL protein been implicated in any physiological or developmental processes?

The physiological and developmental roles of the ANTXRL protein are still not well-defined. However, based on its structural similarity to the anthrax toxin receptor, it is presumed to have functions in cellular trafficking, membrane dynamics, and potentially embryonic development.

Where is the ANTXRL protein typically localized within cells?

The ANTXRL protein is primarily localized to the cell membrane, particularly in the plasma membrane and endomembrane compartments. It may also be found in intracellular vesicles and organelles.

Does ANTXRL protein have any known functional domains or motifs?

The ANTXRL protein contains several conserved domains and motifs, including an extracellular von Willebrand factor A (vWA) domain, a transmembrane domain, and a cytoplasmic domain. These domains suggest potential roles in ligand binding, membrane anchoring, and intracellular signaling.

Are there any known diseases or conditions associated with ANTXRL protein dysregulation?

Currently, there is limited information available about the potential association of ANTXRL protein dysregulation with specific diseases or conditions. Further research is needed to explore potential links between ANTXRL protein and human health.

Are there any known interactions or binding partners of the ANTXRL protein?

The ANTXRL protein is known to interact with other proteins involved in endocytosis and membrane trafficking, such as clathrin and AP-2. It also interacts with the extracellular matrix protein thrombospondin-1. These interactions suggest potential roles in cellular processes such as receptor internalization and cell adhesion.

Are there any drugs or potential therapeutic targets related to the ANTXRL protein?

Currently, there are no known drugs or therapeutic targets directly related to the ANTXRL protein. However, further research on its function and interactions may provide insights that could potentially lead to the development of targeted therapies or treatment strategies.