Active Recombinant Human BMP2, HIgG1 Fc-tagged, mutant
Cat.No. : | BMP2-56H |
Product Overview : | The extracellular domain of human BMP-2 (NP_001191.1) (Arg289-Arg396) is fused to the N-terminus of the Fc region of a mutant human IgG1 was expressed in CHO cell. |
- Specification
- Gene Information
- Related Products
Description : | The protein encoded by this gene belongs to the transforming growth factor-beta (TGFB) superfamily. The encoded protein acts as a disulfide-linked homodimer and induces bone and cartilage formation |
Source : | CHO cells |
Species : | Human |
Tag : | HIgG1 Fc-tagged, mutant |
Form : | Lyophilized from 0.2μm-filtered solution in PBS. |
Bio-activity : | Measured by its ability to induce alkaline phosphatase production by ATDC5 mouse chondrogenic cells. |
Molecular Mass : | 42 KDa (monomer) |
AA Sequence : | Arg289-Arg396 |
Endotoxin : | <0.06 eu/μg as determined by lal>0.06> |
Purity : | >98%, by SDS-PAGE under reducing conditions. |
Stability : | Stable for at least 1 year after receipt when stored at -20°C. Working aliquots are stable for up to 3 months when stored at -20°C. |
Reconstitution : | Reconstitute at 100μg/ml in sterile PBS. |
Warning : | Avoid freeze/thaw cycles. |
Gene Name : | BMP2 bone morphogenetic protein 2 [ Homo sapiens ] |
Official Symbol : | BMP2 |
Synonyms : | BMP2; bone morphogenetic protein 2; BMP2A; BMP-2A; bone morphogenetic protein 2A; BDA2; |
Gene ID : | 650 |
mRNA Refseq : | NM_001200 |
Protein Refseq : | NP_001191 |
MIM : | 112261 |
UniProt ID : | P12643 |
Chromosome Location : | 20p12 |
Pathway : | Adipogenesis, organism-specific biosystem; BMP Signalling Pathway, organism-specific biosystem; Basal cell carcinoma, organism-specific biosystem; Basal cell carcinoma, conserved biosystem; Cytokine-cytokine receptor interaction, organism-specific biosystem; Cytokine-cytokine receptor interaction, conserved biosystem; Heart Development, organism-specific biosystem; |
Function : | BMP receptor binding; SMAD binding; activin receptor activity, type II; cytokine activity; growth factor activity; phosphatase activator activity; protein binding; protein domain specific binding; protein heterodimerization activity; protein homodimerizat |
Products Types
◆ Recombinant Protein | ||
BMP2-654R | Recombinant Rat BMP2 Protein, His (Fc)-Avi-tagged | +Inquiry |
BMP2-16H | Active Recombinant Human/Mouse/Rat/Rhesus/Canine BMP2 protein(Gln283-Arg396), hFc-tagged | +Inquiry |
BMP2-1052M | Recombinant Mouse BMP2 Protein, His (Fc)-Avi-tagged | +Inquiry |
BMP2-011H | Active Recombinant Human BMP2 Protein | +Inquiry |
BMP2-437B | Active Recombinant Human BMP2 Protein | +Inquiry |
◆ Lysates | ||
BMP2-3075HCL | Recombinant Human BMP2 cell lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
Inquiry
0
Inquiry Basket