Recombinant Human FASN, GST-tagged
Cat.No. : | FASN-21H |
Product Overview : | Recombinant Human FASN(2378 a.a. - 2477 a.a.), fused with GST-tag at N-terminal, was expressed in wheat germ. |
- Specification
- Gene Information
- Related Products
Description : | The enzyme encoded by this gene is a multifunctional protein. Its main function is to catalyze the synthesis of palmitate from acetyl-CoA and malonyl-CoA, in the presence of NADPH, into long-chain saturated fatty acids. In some cancer cell lines, this protein has been found to be fused with estrogen receptor-alpha (ER-alpha), in which the N-terminus of FAS is fused in-frame with the C-terminus of ER-alpha. |
Source : | Wheat germ |
Species : | Human |
Tag : | GST |
Molecular Mass : | 36.74 kDa |
AA Sequence : | MEHNRVLEALLPLKGLEERVAAAVD LIIKSHQGLDRQELSFAARSFYYKL RAAEQYTPKAKYHGNVMLLRAKTGG AYGEDLGADYNLSQVCDGKVSVHVI |
Applications : | ELISA; WB-Re; AP; Array |
Storage : | Store at -80°C. Aliquot to avoid repeated freezing and thawing. |
Storage Buffer : | 50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer. |
Gene Name : | FASN fatty acid synthase [ Homo sapiens ] |
Official Symbol : | FASN |
Synonyms : | FASN; fatty acid synthase; FAS; SDR27X1; short chain dehydrogenase/reductase family 27X; member 1; |
Gene ID : | 2194 |
mRNA Refseq : | NM_004104 |
Protein Refseq : | NP_004095 |
MIM : | 600212 |
UniProt ID : | P49327 |
Chromosome Location : | 17q25 |
Pathway : | AMPK signaling; Activation of gene expression by SREBF (SREBP); Defective AMN causes hereditary megaloblastic anemia 1 |
Function : | 3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity; 3-oxoacyl-[acyl-carrier-protein] synthase activity; [acyl-carrier-protein] S-acetyltransferase activity |
Products Types
◆ Recombinant Protein | ||
FASN-718H | Recombinant Human FASN Protein, His/GST-tagged | +Inquiry |
FASN-717C | Recombinant Chicken FASN Protein, His-tagged | +Inquiry |
Fasn-720R | Recombinant Rat Fasn Protein, His-tagged | +Inquiry |
Fasn-719M | Recombinant Mouse Fasn Protein, His-tagged | +Inquiry |
FASN-2924H | Recombinant Human FASN Protein, His (Fc)-Avi-tagged | +Inquiry |
◆ Lysates | ||
FASN-597HCL | Recombinant Human FASN cell lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
Inquiry
0
Inquiry Basket