Native Human Lipoprotein

• Cat.No.: LDLR-85H

Specification

• Description: In a normal fasting individual, low density lipoprotein concentrations range from 2.0 - 3.5 g/L. LDL constitutes 50% of the total lipoprotein mass in plasma and is the major carrier of cholesterol and cholesteryl esters. LDL levels strongly correlate with coronary heart disease.
• Source: Human plasma
• Species: Human
• Form: Liquid
• Molecular Mass: 2,300.0 kDa
• Purity: Purity by SDS-PAGE: ≥95%; Purity by HPLC: ≥95%
• Usage: For Research Use Only! Not For Use in Humans.
• Notes: Centrifuge the vial prior to opening
• Storage: 4°C
• Storage Buffer: 250 μl liquid in 150 mM NaCl, pH 7.4, and 0.01% EDTA
• Shipping: Gel pack

Gene Information

• Gene Name: LDLR low density lipoprotein receptor [ Homo sapiens ]
• Official Symbol: LDLR
• Synonyms: LDLR; low density lipoprotein receptor; low-density lipoprotein receptor; familial hypercholesterolemia; LDL receptor; low-density lipoprotein receptor class A domain-containing protein 3; FH; FHC; LDLCQ2
• Gene ID: 3949
• mRNA Refseq: NM_000527
• Protein Refseq: NP_000518
• MIM: 606945
• UniProt ID: P01130
• Chromosome Location: 19p13.2
• Pathway: Bile secretion, organism-specific biosystem; Bile secretion, conserved biosystem; Chylomicron-mediated lipid transport, organism-specific biosystem; DNA damage response (only ATM dependent), organism-specific biosystem; Endocytosis, organism-specific biosystem; Endocytosis, conserved biosystem; Hepatitis C, organism-specific biosystem
• Function: calcium ion binding; glycoprotein binding; low-density lipoprotein receptor activity; protein binding; receptor activity; very-low-density lipoprotein particle receptor activity