Recombinant Chicken DCK

• Cat.No.: DCK-1591C
• Product Overview: Recombinant Chicken DCK full length or partial length protein was expressed.

Specification

• Source: Mammalian Cells
• Species: Chicken
• Tag: His
• Form: Liquid or lyophilized powder
• Endotoxin: < 1.0 eu per μg of the protein as determined by the LAL method.
• Purity: >80%
• Notes: This item requires custom production and lead time is between 5-9 weeks. We can custom produce according to your specifications.
• Storage: Store it at +4 oC for short term. For long term storage, store it at -20 oC～-80 oC.
• Storage Buffer: PBS buffer

Gene Information

• Gene Name: DCK deoxycytidine kinase [ Gallus gallus (chicken) ]
• Official Symbol: DCK
• Gene ID: 422648
• Protein Refseq: NP_001006451
• UniProt ID: Q5ZMF3

Reviews

08/05/2020

Worked as expected, pure.

07/01/2020

Excellent for research, quality.

07/26/2018

Fast shipping, reliable product.

Q&As

How is DCK implicated in resistance to chemotherapy?

Reduced DCK activity or expression can lead to resistance against nucleoside analog-based chemotherapy.

What therapeutic strategies are being explored to modulate DCK activity?

Strategies include modulating DCK levels to overcome drug resistance and improve treatment outcomes.

What is the significance of DCK in the action of certain chemotherapeutic agents?

DCK activation of prodrugs enhances their cytotoxicity, improving chemotherapeutic efficacy.

Are there known genetic variants of DCK associated with different responses to treatment?

Genetic variants in DCK have been linked to varied responses to nucleoside analog drugs.

How does DCK contribute to nucleoside metabolism?

It phosphorylates deoxyribonucleosides, contributing to their conversion to active triphosphate forms.

In which types of cells or tissues is DCK predominantly expressed?

DCK is widely expressed but shows higher activity in proliferating cells and certain tissues like the liver.

What is the primary role of DCK in cellular processes?

DCK plays a crucial role in activating nucleoside analog prodrugs.