Recombinant Human monoamine oxidase B,His-tagged
Cat.No. : |
MAOB-107H |
Product Overview : |
Recombinant Human MAO-B comprises a 488 amino acid fragment (2-489) corresponding to the cytoplasmic domain fragment of the mature MAO-B protein and is expressed in E. coli with an amino-terminal hexahistidine tag. |
- Specification
- Gene Information
- Related Products
Cat. No. : |
MAOB-107H |
Description : |
Monoamine oxidase B (MAO-B) is a flavin-containing mitochondrial enzyme, which catalyzes the oxidative deamination of biogenic and xenobiotic monoamines. It regulates the metabolic degradation of catecholamines and serotonin in neural and other target tissues. MAO-B is found platelets and in dopamine-secreting neurons in the brain. Increased levels of MAO B that have been identified in brain of Alzheimer's patients. Monoamine oxidases (MAO B and MAO A) are well-known targets for antidepressant drugs and for drugs used to treat neurological disorders and aging diseases, such as Parkinson's and Alzheimer's disease. |
Source : |
E.coli. |
Purity : |
>95% by SDS-PAGE |
Form : |
Liquid |
Storage : |
Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. Please avoid freeze thaw cycles. |
Gene Name : |
MAOB monoamine oxidase B [ Homo sapiens ] |
Synonyms : |
MAOB; MGC26382; monoamine oxidase B; MAO, brain; MAO, platelet; tyramine oxidase; adrenalin oxidase; EC 1.4.3.4; MAO-B. |
Gene ID : |
4129 |
mRNA Refseq : |
NM_000898 |
Protein Refseq : |
NP_000889 |
MIM : |
309860 |
UniProt ID : |
P27338.3 |
Chromosome Location : |
Xp11.23 |
Pathway : |
Glycine, serine and threonine metabolism; Histidine metabolism; Phenylalanine metabolism; Tryptophan metabolism; Tyrosine metabolism; Urea cycle and metabolism of amino groups; Biological oxidations |
Function : |
amine oxidase activity; electron carrier activity; oxidoreductase activity |
Products Types
Related Gene
MAOB
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