Active Recombinant Mouse Fn-14, Fc-tagged

• Cat.No.: Tnfrsf12a-42M
• Product Overview: Produced in HEK 293 cells. The extracellular domain of mouse Fn14 (aa 1-75) is fused to the Fc portion of human IgG1.

Specification

• Source: HEK 293 cells
• Species: Mouse
• Tag: Fc
• Form: Lyophilized. Contains PBS. Reconstitute with 50 μL of sterile water for a 1 mg/mL solution. Further dilutions should be made with medium containing 5% fetal calf serum. After reconstitution, prepare aliquots and store at -20°C.
• Bio-activity: Inhibits TWEAK-mediated killing of Kym-1 target cells. Binds to human and mouse TWEAK.
• Molecular Mass: ~34 kDa as determined by SDS-PAGE
• Endotoxin: <0.1 eu/μg of purified protein (lal test).>
• Purity: >95% as determined by SDS-PAGE.
• Usage: For in vitro research use only. Not for use in diagnostics or in humans.
• Storage: Store at -20°C. After reconstitution, prepare aliquots and store at -20°C.
• Warning: No warranties, expressed or implied, are made regarding the use of this product. Creative Biomart is not liable for any damage, personal injury, or economic loss caused by this product.

Gene Information

• Gene Name: Tnfrsf12a tumor necrosis factor receptor superfamily, member 12a [ Mus musculus ]
• Official Symbol: Tnfrsf12a
• Synonyms: TNFRSF12A; tumor necrosis factor receptor superfamily, member 12a; tumor necrosis factor receptor superfamily member 12A; tweak-receptor; FGF-inducible 14; type I transmembrane protein Fn14; fibroblast growth factor regulated protein 2; fibroblast growth factor-regulated protein 2; fibroblast growth factor-inducible immediate-early response protein 14; Fn14; HPIP; C87282; TweakR; TWEAK-R; AI255180
• Gene ID: 27279
• mRNA Refseq: NM_001161746
• Protein Refseq: NP_001155218
• Pathway: Cytokine-cytokine receptor interaction, organism-specific biosystem; Cytokine-cytokine receptor interaction, conserved biosystem
• Function: protein binding; receptor activity