Active Recombinant Human CLEC4M, Fc Chimera

• Cat.No.: CLEC4M-689H
• Product Overview: Recombinant Human CLEC4M (Accession # NP_001138382) was produced in Mouse myeloma cell line, NS0-derived.

Specification

• Source: Mammalian cells
• Species: Human
• Tag: Fc Chimera
• Predicted N Terminal: Met
• Form: Lyophilized from a 0.2 µm filtered solution in Tris-Citrate.
• Bio-activity: Measured by the ability of the immobilized protein to support the adhesion of ICAM-3 expressing CHO Chinese hamster ovary cells.When 5 x 10^4 cells/well are added to rhDC-SIGNR/Fc coated plates (5 µg/mL with 100 µL/well), approximately 40% - 70% of added cells will adhere after 1 hour at room temperature. Optimal dilutions should be determined by each laboratory for each application.
• Molecular Mass: Recombinant Human CLEC4M, Fc Chimera has a calculated MW of 61.4 kDa (monomer). In SDS-PAGE migrates as 61-66 kDa, reducing conditions.
• Purity: >80%, by SDS-PAGE under reducing conditions and visualized by silver stain.
• Storage: Avoid repeated freeze-thaw cycles. No activity loss was observed after storage at: In lyophilized state for 1 year (4ºC); After reconstitution under sterile conditions for 3 months (-70ºC).

Gene Information

• Gene Name: CLEC4M C-type lectin domain family 4, member M [ Homo sapiens ]
• Official Symbol: CLEC4M
• Synonyms: CLEC4M; C-type lectin domain family 4, member M; CD209L, CD299, CD299 antigen; C-type lectin domain family 4 member M; DC SIGN2; DC SIGNR; DCSIGNR; HP10347; LSIGN; CD299 antigen; DC-SIGN-related protein; CD209 antigen-like protein 1; mannose binding C-type lectin DC-SIGNR; dendritic cell-specific ICAM-3-grabbing non-integrin 2; liver/lymph node-specific ICAM-3 grabbing non-integrin; liver/lymph node-specific ICAM-3-grabbing non-integrin; CD299; CD209L; L-SIGN; DC-SIGN2; DC-SIGNR; MGC47866; MGC129964
• Gene ID: 10332
• mRNA Refseq: NM_001144904
• Protein Refseq: NP_001138376
• MIM: 605872
• UniProt ID: Q9H2X3
• Chromosome Location: 19p13