Active Recombinant Mouse Tnfrsf17 Protein, Fc Chimera

• Cat.No.: Tnfrsf17-661M
• Product Overview: Recombinant Mouse Tnfrsf17 (Accession # NP_035738), fused with , was produced in Mouse myeloma cell line, NS0-derived.

Specification

• Source: Mammalian cells
• Species: Mouse
• Tag: Fc
• Predicted N Terminal: Met1
• Form: Lyophilized from a 0.2 µm filtered solution in MES and NaCl.
• Bio-activity: Measured by its ability to inhibit APRIL-mediated proliferation of anti-IgM stimulated mouse B cells. Moore, P.A. et al. (1999) Science 285:260; Gross, J.A. et al. (2000) Nature 404:995; Schneider, P. et al. (1999) J. Exp. Med. 189:1747.The ED50 for this effect is typically 0.01-0.03 µg/mL in the presence of 100 ng/mL of rhAPRIL.
• Molecular Mass: Recombinant Mouse Tnfrsf17, Fc Chimera has a calculated MW of 32 kDa (monomer). In SDS-PAGE migrates as 35-40 kDa, reducing conditions.
• Purity: >95%, by SDS-PAGE under reducing conditions and visualized by silver stain.
• Storage: Avoid repeated freeze-thaw cycles. No activity loss was observed after storage at: In lyophilized state for 1 year (4ºC); After reconstitution under sterile conditions for 3 months (-70ºC).

Gene Information

• Gene Name: Tnfrsf17 tumor necrosis factor receptor superfamily, member 17 [ Mus musculus ]
• Official Symbol: Tnfrsf17
• Synonyms: TNFRSF17; tumor necrosis factor receptor superfamily, member 17; tumor necrosis factor receptor superfamily member 17; B-cell maturation protein; BCM; BCMA; Tnfrsf13; Tnfrsf13a
• Gene ID: 21935
• mRNA Refseq: NM_011608
• Protein Refseq: NP_035738