Active Recombinant Rat Fas Protein, Fc Chimera

• Cat.No.: Fas-823R
• Product Overview: Recombinant Rat Fas (Accession # NP_631933), fused with , was produced in Mouse myeloma cell line, NS0-derived.

Specification

• Source: Mammalian cells
• Species: Rat
• Tag: Fc
• Predicted N Terminal: No results obtained: Gln22 predicted
• Form: Lyophilized from a 0.2 µm filtered solution in PBS.
• Bio-activity: Measured by its ability to inhibit Fas Ligand-induced apoptosis of Jurkat human acute T cell leukemia cells. Cheng, J. et al. (1994) Science 263:1759.The ED50 for this effect is typically 0.05 - 0.25 µg/mL in the presence of 100 ng/mL recombinant rat Fas Ligand.
• Molecular Mass: Recombinant Rat Fas, Fc Chimera has a calculated MW of 43.3 kDa (monomer). In SDS-PAGE migrates as 60-65 kDa, reducing conditions.
• Purity: >90%, by SDS-PAGE under reducing conditions and visualized by silver stain.
• Storage: Avoid repeated freeze-thaw cycles. No activity loss was observed after storage at: In lyophilized state for 1 year (4ºC); After reconstitution under sterile conditions for 3 months (-70ºC).

Gene Information

• Gene Name: Fas Fas (TNF receptor superfamily, member 6) [ Rattus norvegicus ]
• Official Symbol: Fas
• Synonyms: FAS; Fas (TNF receptor superfamily, member 6); tumor necrosis factor receptor superfamily member 6; CD95 antigen; Fas receptor; apo-1 antigen; FASLG receptor; Fas antigen (ATP1); apoptosis-mediating surface antigen FAS; Tumor necrosis factor receptor superfamily, member 6; Tnfrsf6
• Gene ID: 246097
• mRNA Refseq: NM_139194
• Protein Refseq: NP_631933