Active Recombinant Human FLT1, Fc-tagged
Cat.No. : | FLT1-616H |
Product Overview : | The recombinant human FLT1-Fc fusion is expressed as a 859 amino acid protein consisting of Ser27 - Arg656 region of FLT1 (Uniprot accession # P17948 - isoform 2 or soluble FLT1) and a C-terminal Fc from human IgG1, which exists as a dimer under non-reducing conditions. |
- Specification
- Gene Information
- Related Products
Source : | Human cells |
Species : | Human |
Tag : | Fc |
Form : | Supplied at 0.5 mg/ml in sterile PBS pH7.4 (carrier free). |
Bio-activity : | Binds VEGF and inhibits VEGF-dependent proliferation of human umbilical vein endothelial cells (HUVEC) |
Molecular Mass : | Calculated molecular mass (kDa): 96.9; Estimated by SDS-PAGE under reducing condition (kDa): 110-120 |
AA Sequence : | SKLKDPELSLKGTQHIMQAGQTLHL QCRGEAAHKWSLPEMVSKESERLSI TKSACGRNGKQFCSTLTLNTAQAN HTGFYSCKYLAVPTSKKKETESAIY IFISDTGRPFVEMYSEIPEIIHMTE GRELVIPCRVTSPNITVTLKKFPL DTLIPDGKRIIWDSRKGFIISNATY KEIGLLTCEATVNGHLYKTNYLTHR QTNTIIDVQISTPRPVKLLRGHTL VLNCTATTPLNTRVQMTWSYPDEKN KRASVRRRIDQSNSHANIFYSVLTI DKMQNKDKGLYTCRVRSGPSFKSV NTSVHIYDKAFITVKHRKQQVLETV AGKRSYRLSMKVKAFPSPEVVWLKD GLPATEKSARYLTRGYSLIIKDVT EEDAGNYTILLSIKQSNVFKNLTAT LIVNVKPQIYEKAVSSFPDPALYPL GSRQILTCTAYGIPQPTIKWFWH PCNHNHSEARCDFCSNNEESFILDA DSNMGNRIESITQRMAIIEGKNKMA STLVVADSRISGIYICIASNKVGT VGRNISFYITDVPNGFHVNLEKMPT EGEDLKLSCTVNKFLYRDVTWILLR TVNNRTMHYSISKQKMAITKEHSI TLNLTIMNVSLQDSGTYACRARNVY TGEEILQKKEITIRGSTGTHTCPPC PAPELLGGPSVFLFPPKPKDTLMI SRTPEVTCVVVDVSHEDPEVKFNWY VDGVEVHNAKTKPREEQYNSTYRVV SVLTVLHQDWLNGKEYKCKVSNKA LPAPIEKTISKAKGQPREPQVYTLP PSREEMTKNQVSLTCLVKGFYPSDI AVEWESNGQPENNYKTTPPVLDS DGSFFLYSKLTVDKSRWQQGNVFSC SVMHEALHNHYTQKSLSLSPGK |
Endotoxin : | <0.1 eu per 1 μg of purified recombinant protein determined by the lal>0.1> |
Purity : | >95% judged by SDS-PAGE under reducing condition |
Storage : | The product is shipped at 4°C. Upon receipt, centrifuge the product briefly before opening the vial. It is recommended to store small aliquots at the temperature below –20°C for long-term storage and the product is stable for 3 months. The undiluted protein can be stored at 4°C for no more than 2 weeks. Avoid repeated freeze-thaw cycles. |
Gene Name : | FLT1 fms-related tyrosine kinase 1 (vascular endothelial growth factor/vascular permeability factor receptor) [ Homo sapiens ] |
Official Symbol : | FLT1 |
Synonyms : | FLT1; fms-related tyrosine kinase 1 (vascular endothelial growth factor/vascular permeability factor receptor); FLT; vascular endothelial growth factor receptor 1; VEGFR1; FLT-1; VEGFR-1; fms-like tyrosine kinase 1; tyrosine-protein kinase FRT; tyrosine-protein kinase receptor FLT; vascular permeability factor receptor; |
Gene ID : | 2321 |
mRNA Refseq : | NM_001159920 |
Protein Refseq : | NP_001153392 |
MIM : | 165070 |
UniProt ID : | P17948 |
Chromosome Location : | 13q12 |
Pathway : | Cytokine-cytokine receptor interaction, organism-specific biosystem; Cytokine-cytokine receptor interaction, conserved biosystem; Endocytosis, organism-specific biosystem; Endocytosis, conserved biosystem; Focal Adhesion, organism-specific biosystem; Focal adhesion, organism-specific biosystem; Focal adhesion, conserved biosystem; |
Function : | ATP binding; growth factor binding; nucleotide binding; protein binding; receptor activity; transmembrane receptor protein tyrosine kinase activity; vascular endothelial growth factor-activated receptor activity; vascular endothelial growth factor-activated receptor activity; |
Products Types
◆ Recombinant Protein | ||
FLT1-1314H | Recombinant Human FLT1 Protein (P801-L1158), His tagged | +Inquiry |
FLT1-133H | Active Recombinant Human FLT1 Protein (27-328aa), C-hIgG tagged | +Inquiry |
FLT1-3810H | Active Recombinant Human FLT1 Protein, His-Avi-tagged, Biotinylated | +Inquiry |
FLT1-923H | Recombinant Human FLT1 Protein, His (Fc)-Avi-tagged | +Inquiry |
FLT1-4367H | Active Recombinant Human FLT1 Protein, GST-tagged | +Inquiry |
◆ Lysates | ||
FLT1-1207RCL | Recombinant Rat FLT1 cell lysate | +Inquiry |
FLT1-1909HCL | Recombinant Human FLT1 cell lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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