Active Recombinant Human TNFRSF18, Fc-tagged, Biotinylated
Cat.No. : | TNFRSF18-618H |
Product Overview : | The recombinant human GITR-Fc fusion is expressed as a 364 amino acid protein consisting of Gln26 - Glu161 region of GITR (UniProt accession #Q9Y5U5) and a C-terminal Fc from human IgG1, which exists as a dimer under non-reducing conditions. |
- Specification
- Gene Information
- Related Products
Source : | Human cells |
Species : | Human |
Tag : | Fc |
Form : | Supplied at 0.5 mg/ml in sterile PBSpH7.4 (carrier & preservative free). The purified recombinant protein was labeled with Biotin (3-5 Biotin per molecule). |
Bio-activity : | Binds to its ligand GITRL/TNFSF18 and blocks GITRL-induced signaling activity. |
Molecular Mass : | Calculated molecular mass (kDa): 40.1; Estimated by SDS-PAGE under reducing condition (kDa): 45-50 |
Endotoxin : | <0.1 eu per 1 μg of purified recombinant protein determined by the lal>0.1> |
Purity : | >95% judged by SDS-PAGE under reducing condition |
Storage : | The product is shipped at 4°C. Upon receipt, centrifuge the product briefly before opening the vial. It is recommended to store small aliquots at the temperature below –20°C for long-term storage and the product is stable for 3 months. The undiluted protein can be stored at 4°C for no more than 2 weeks. Avoid repeated freeze-thaw cycles. |
Gene Name : | TNFRSF18 tumor necrosis factor receptor superfamily, member 18 [ Homo sapiens ] |
Official Symbol : | TNFRSF18 |
Synonyms : | TNFRSF18; tumor necrosis factor receptor superfamily, member 18; tumor necrosis factor receptor superfamily member 18; AITR; CD357; GITR; activation-inducible TNFR family receptor; glucocorticoid-induced TNFR-related protein; TNF receptor superfamily activation-inducible protein; GITR-D; |
Gene ID : | 8784 |
mRNA Refseq : | NM_004195 |
Protein Refseq : | NP_004186 |
MIM : | 603905 |
UniProt ID : | Q9Y5U5 |
Chromosome Location : | 1p36.3 |
Pathway : | Cytokine-cytokine receptor interaction, organism-specific biosystem; Cytokine-cytokine receptor interaction, conserved biosystem; Downstream signaling in naive CD8+ T cells, organism-specific biosystem; |
Function : | binding; receptor activity; tumor necrosis factor-activated receptor activity; |
Products Types
◆ Recombinant Protein | ||
TNFRSF18-663M | Recombinant Mouse TNFRSF18 Protein, Fc-tagged | +Inquiry |
TNFRSF18-1995H | Recombinant Human TNFRSF18 Protein, MYC/DDK-tagged | +Inquiry |
TNFRSF18-665R | Recombinant Rat TNFRSF18 Protein, Fc-tagged | +Inquiry |
TNFRSF18-1019C | Recombinant Cynomolgus TNFRSF18 Protein (Met1-Glu155), His-tagged | +Inquiry |
TNFRSF18-661H | Recombinant Human TNFRSF18 Protein | +Inquiry |
◆ Lysates | ||
TNFRSF18-1245RCL | Recombinant Rat TNFRSF18 cell lysate | +Inquiry |
TNFRSF18-1143HCL | Recombinant Human TNFRSF18 cell lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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