Active Recombinant Human AMBP

• Cat.No.: AMBP-230H
• Product Overview: Recombinant Ulinastatin produced in Yeast is a single, glycosylated, polypeptide having 143 amino acids, molecular mass of 20 kDa and predicted pI of 4.5.

Specification

• Description: This gene encodes a complex glycoprotein secreted in plasma. The precursor is proteolytically processed into distinct functioning proteins: alpha-1-microglobulin, which belongs to the superfamily of lipocalin transport proteins and may play a role in the regulation of inflammatory processes, and bikunin, which is a urinary trypsin inhibitor belonging to the superfamily of Kunitz-type protease inhibitors and plays an important role in many physiological and pathological processes. This gene is located on chromosome 9 in a cluster of lipocalin genes.
• Source: Pichia Pastoris.
• Species: Human
• Form: Sterile Filtered solution. Formulated in 1X PBS.
• Bio-activity: Greater than 3000U/mg as measured by BAEE method.
• Molecular Mass: 20 kDa
• AA Sequence: AVLPQEEEGS GGGQLVTEVT KKEDSCQLGY SAGPCMGMTS RYFYNGTSMACETFQYGGCM GNGNNFVTEK ECLQTCRTVA ACNLPIVRGP CRAFIQLWAFDAVKGKCVLF PYGGCQGNGN KFYSEKECRE YCGVPGDGDE ELL.
• Purity: Greater than 98.0% as determined by RP-HPLC and FPLC.
• Storage: Ulinastatin although stable at 15°C for 2 weeks, should be stored below -18°C. Please prevent freeze-thaw cycles.
• Publication:
  Mimicking filtration and transport of rotavirus and adenovirus in sand media using DNA-labeled, protein-coated silica nanoparticles. (2014)

Gene Information

• Gene Name: AMBP alpha-1-microglobulin/bikunin precursor [ Homo sapiens (human) ]
• Official Symbol: AMBP
• Synonyms: AMBP; A1M; HCP; ITI; UTI; EDC1; HI30; ITIL; IATIL; ITILC; alpha-1-microglobulin/bikunin precursor; protein AMBP; bikunin; uristatin; protein HC; trypstatin; uronic-acid-rich protein; growth-inhibiting protein 19; inter-alpha-trypsin inhibitor light chain; complex-forming glycoprotein heterogeneous in charge
• Gene ID: 259
• mRNA Refseq: NM_001633
• Protein Refseq: NP_001624
• MIM: 176870
• UniProt ID: P02760
• Chromosome Location: 9q32-q33
• Pathway: Binding and Uptake of Ligands by Scavenger Receptors; Scavenging of Heme from Plasma
• Function: IgA binding; calcium channel inhibitor activity; calcium oxalate binding