Catalog # or name ...
Human UTI produced in Yeast is a single, glycosylated,
polypeptide. The protein contains 143 amino acids and has a
molecular mass of 20 kDa and predicted pI of 4.5.
Inhibitor is a glucoprotein proteinase inhibitor with a
molecular weight of about 67,000 derived from human urine which
inhibits the activity of trypsin, chymotrypsin, lactate, lipase,
hyaluronidase and various pancreatic enzymes. Ulinastatin is has
strong inhibition effect to various protease, sugar and fat
hydrolase. Ulinastatin precursor is proteolytically processed
into distinct functioning proteins. Uristatin gene is located on
chromosome 9 in a cluster of lipocalin genes. Bikunin localizes
cell membrane. Free uristatin and bikunin pass readily into
urine and are primarily bound to heavy chains that constitute
the proinhibitor form in plasma. Ulinastatin particularly
interacts with ORF3 protein of hepatitis E virus and in charge
for enhancing alpha microglobulin export from the hepatocyte.
GGGQLVTEVT KKEDSCQLGY SAGPCMGMTS RYFYNGTSM ACETFQYGGCM
GNGNNFVTEK ECLQTCRTVA ACNLPIVRGP CRAFIQLWA FDAVKGKCVLF
PYGGCQGNGN KFYSEKECRE YCGVPGDGDE ELL
98.0% as determined by: (a) Analysis by RP-HPLC. (b)
3000U/mg as measred by BAEE method.
although stable at 15oC
for 2 weeks, should be stored desiccated below -18oC.
Please prevent freeze-thaw cycles.
AMBP alpha-1-microglobulin/bikunin precursor [ Homo sapiens ]
Ulinastatin; Alpha-1-microglobulin/bikunin precursor; HCP; ITI;
UTI; EDC1; HI30; ITIL; IATIL; ITILC; Bikunin; Uristatin; Protein
HC; Trypstatin; Uronic-acid-rich protein; Growth-inhibiting
protein 19; Inter-alpha-trypsin inhibitor light chain;
Complex-forming glycoprotein heterogeneous in charge;
calcium channel inhibitor activity; calcium oxalate binding;
heme binding; peptidase inhibitor activity; transporter
activity; serine-type endopeptidase inhibitor activity; protein
PDB rendering based on 1bik.
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