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Recombinant Human Zinc Finger, GATA-like Protein 1

Cat.No. : ZGLP1-941H
Product Overview : Recombinant human GLP-1 produced inE.coliis a 3.3 kDa consisting of 31 amino acid residues.
  • Specification
  • Gene Information
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Cat. No. : ZGLP1-941H
Description : GLP-1 is a proglucagon-derived peptide hormone secreted primarily by intestinal L cells during feeding. Its major physiological function is stimulation of pancreatic β-cells to release appropriate amounts of insulin after glucose absorption. Other biological actions exhibited by GLP-1 include suppression of plasma glucagons levels, inhibition of gastric motility, and promotion of satiety. The secretion of GLP-1 from intestinal L cells is stimulated by nutrients, hormones, and neural inputs. On the other hand, insulin has been reported to inhibit GLP-1 release, indicating that a feedback loop mechanism regulates GLP-1 secretion. In addition to being the precursor of GLP-1, proglucagon, whose primary structure is highly conserved in mammalian species, is also the precursor for other members of the glucagon family of peptide hormones including glicentin-related pancreatic peptide (GRPP), glucagons, and GLP-2.
Source : E.coli.
Purity : 98 % (SDS-PAGE, HPLC).
Endotoxin level : < 0.1 ng per ug of GLP-1.
Stabilizer : None.
Formulation : Lyophilized.
Biologically Activity : Data not available!
Stability : The lyophilized protein is stable for at least 2 years from date of receipt at -20°C. Reconstituted GLP-1 is stable for at least 3 months when stored in working aliquots with a carrier protein at -20°C. Avoid repeated freeze-thaw cycles.
Gene Name : ZGLP1 zinc finger, GATA-like protein 1 [ Homo sapiens ]
Synonyms : ZGLP1; zinc finger, GATA-like protein 1; GLP1; GLP-1; FLJ39511; FLJ39703; GATA like protein 1
Gene ID : 100125288
mRNA Refseq : NM_001103167
Protein Refseq : NP_001096637
MIM : 611639
UniProt ID : P0C6A0
Chromosome Location : 19p13.2
Function : metal ion binding; sequence-specific DNA binding; transcription factor activity; transcription repressor activity; zinc ion binding

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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