Recombinant Mouse Tnfsf14

• Cat.No.: Tnfsf14-948M
• Product Overview: Recombinant mouse LIGHT produced inE.Coliis a 20.1 kDa protein containing 183 amino acid residues.

Specification

• Cat. No.: Tnfsf14 -948M
• Description: LIGHT belongs to the TNF family of ligands, and can signal through the herpes virus entry mediator type A receptor (HVEM, TNFRSF14), LT-beta-R, or bind to a decoy receptor, DcR3. It is expressed in splenocytes, activated PBL, CD+8 tumor infiltrating lymphocytes, granulocytes, and monocytes. LIGHT has the ability to active NFkB, to co-stimulate the activation of lymphocytes and to induce apoptosis in certain human tumor cells.
• Source: E.Coli.
• Purity: > 98% by SDS-PAGE and HPLC analysis.
• Endotoxin Level: < 0.1 ng per μg of LIGHT.
• Stabilizer: None.
• Formulation: Lyophilized.
• Biological Activity: Testing in Progress!
• Reconstitution: Reconstitute in water to a concentration of 0.1-1.0 mg/ml. This solution can be diluted into other aqueous buffers and stored at 4°C for 1 week or -20°C for future use.
• Stability: The lyophilized protein is stable for a least 2 years from date of receipt at -20°C. Reconstituted LIGHT is stable for at least 3 months when stored in working aliquots with carrier protein at -20°C. Avoid repeated freeze-thaw cycles.

Gene Information

• Gene Name: Tnfsf14 tumor necrosis factor (ligand) superfamily, member 14 [ Mus musculus ]
• Synonyms: tumor necrosis factor (ligand) superfamily, member 14; LTg; HVEML; LIGHT; Ly113; HVEM-L; Tnfsf14; tumor necrosis factor ligand superfamily, member 14
• Gene ID: 50930
• mRNA Refseq: NM_019418
• Protein Refseq: NP_062291
• UniProt ID: Q9QYH9
• Chromosome Location: 17 D-E1
• Pathway: Cytokine-cytokine receptor interaction
• Function: tumor necrosis factor receptor binding; cytokine activity