Recombinant Human CITED2, His-tagged
Cat.No. : | CITED2-1353H |
Product Overview : | Recombinant Human CITED2 produced inE.Coliis a single, non-glycosylated, polypeptide chain containing 278 amino acids (1-270 a.a.) and having a molecular mass of 29.5 kDa. The CITED2 is fused to 8 amino acids His Tag at C-terminus and purified by proprietary chromatographic techniques. |
- Specification
- Gene Information
- Related Products
Cat. No. : | CITED2-1353H |
Description : | CITED2 is a significant transcriptional cofactor that takes part in multiple organ development. CITED2 is a cAMP-responsive element-binding protein (CBP)/p300 interacting transcriptional modulator and a negative regulator for HIF1A through its competitive binding with HIF1A to CBP/p300. CITED2 is essential for mouse fetal liver hematopoiesis and is necessary for the appropriate formation of the hyaloid vasculature and for lens morphogenesis. CITED2 is a coactivator of HNF4alpha and necessary for liver development. CITED2 is a coactivator of PPAR-alpha and both participate in signaling cascades of hypoxic response and angiogenesis. |
Source : | Escherichia Coli. |
Amino Acid Sequence : | MADHMMAMNH GRFPDGTNGL HHHPAHRMGM GQFPSPHHHQ QQQPQHAFNA LMGEHIHYGA GNMNATSGIR HAMGPGTVNG GHPPSALAPA ARFNNSQFMG PPVASQGGSL PASMQLQKLN NQYFNHHPYP HNHYMPDLHP AAGHQMNGTN QHFRDCNPKH SGGSSTPGGS GGSSTPGGSG SSSGGGAGSS NSGGGSGSGN MPASVAHVPA AMLPPNVIDT DFIDEEVLMS LVIEMGLDRI KELPELWLGQ NEFDFMTDFV CKQQPSRVSC LEHHHHHH. |
Physical Appearance : | Sterile Filtered colorless solution. |
Formulation : | The CITED2 solution contains 20mM Tris pH-8, 1mM DTT, 0.1M NaCl & 40% glycerol. |
Purity : | Greater than 90.0% as determined by SDS-PAGE. |
Stability : | CITED2 although stable 4°C for 4 weeks, should be stored desiccated below -18°C. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA). Please prevent freeze-thaw cycles. |
Gene Name : | CITED2 Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2 [ Homo sapiens ] |
Synonyms : | CITED2; Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2; MRG1; P35SRJ; MSG-related protein 1; P35srj; Cbp/p300-interacting transactivator 2 |
Gene ID : | 10370 |
mRNA Refseq : | NM_006079 |
Protein Refseq : | NP_006070 |
MIM : | 602937 |
UniProt ID : | Q99967 |
Chromosome Location : | 6q23.3 |
Function : | protein binding; transcription coactivator activity; transcription factor activity |
Products Types
◆ Recombinant Protein | ||
Cited2-2169M | Recombinant Mouse Cited2 Protein, Myc/DDK-tagged | +Inquiry |
CITED2-606H | Recombinant Human CITED2 Protein, His (Fc)-Avi-tagged | +Inquiry |
CITED2-1702M | Recombinant Mouse CITED2 Protein, His (Fc)-Avi-tagged | +Inquiry |
CITED2-3247H | Recombinant Human CITED2 Protein, MYC/DDK-tagged | +Inquiry |
CITED2-1387H | Recombinant Human CITED2 Protein, GST-tagged | +Inquiry |
◆ Lysates | ||
CITED2-359HCL | Recombinant Human CITED2 cell lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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