Recombinant Human Carnitine O-octanoyltransferase, GST-tagged, Active
Cat.No. : | CROT-287H |
Product Overview : | Recombinant human COT (30-397) was expressed by baculovirus inSf9 insect cellsusing an N-terminal GST tag. MW= 70 kDa. |
- Specification
- Gene Information
- Related Products
Cat. No. : | CROT-287H |
Description : | COT is an oncogene that can activate both the MAP kinase and JNK kinase pathways. COT activates IkappaB kinases and induces the nuclear production of NF-kappaB. C-terminal catalytic domain of KSR2 associates with COT and KSR2 can negatively regulates the kinase activity of COT in vitro. Co-transfection of KSR2 with COT in cells lead to reduced COT-mediated ERK activation and COT-induced IL8 production in a dose-dependent manner. |
Source : | Sf9 insect cellsusing baculovirus. |
Sequence : | 30-397. |
Applications : | Kinase Assay, Western Blot. |
Storage And Stability : | Store product at –70oC. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. For most favorable performance, avoid repeated handling and multiple freeze/thaw cycles. |
Gene Name : | CROT carnitine O-octanoyltransferase [ Homo sapiens ] |
Synonyms : | CROT; carnitine O-octanoyltransferase; COT; peroxisomal carnitine acyltransferase; peroxisomal carnitine octanoyltransferase; EC 2.3.1.137 |
Gene ID : | 54677 |
mRNA Refseq : | NM_001143935 |
Protein Refseq : | NP_001137407 |
MIM : | 606090 |
UniProt ID : | Q9UKG9 |
Chromosome Location : | 7q21 |
Pathway : | Metabolism of lipids and lipoproteins |
Function : | acyltransferase activity; carnitine O-octanoyltransferase activity; transferase activity |
Products Types
◆ Recombinant Protein | ||
CROT-2122H | Recombinant Human CROT Protein (1-87 aa), GST-tagged | +Inquiry |
CROT-663H | Recombinant Human CROT Protein, His (Fc)-Avi-tagged | +Inquiry |
CROT-3323H | Recombinant Human CROT Protein, MYC/DDK-tagged | +Inquiry |
Crot-2318M | Recombinant Mouse Crot Protein, Myc/DDK-tagged | +Inquiry |
CROT-1988M | Recombinant Mouse CROT Protein, His (Fc)-Avi-tagged | +Inquiry |
◆ Lysates | ||
CROT-516HCL | Recombinant Human CROT cell lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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