Recombinant Human AMBN

• Cat.No.: AMBN-27234TH
• Product Overview: Recombinant full length Human AMBN with N terminal proprrietary tag; Predicted MW 75.24kDa.

Specification

• Description: This gene encodes the nonamelogenin enamel matrix protein ameloblastin. The encoded protein may be important in enamel matrix formation and mineralization. This gene is located in the calcium-binding phosphoprotein gene cluster on chromosome 4. Mutations in this gene may be associated with dentinogenesis imperfect and autosomal dominant amylogenesis imperfect.
• Protein length: 447 amino acids
• Molecular Weight: 75.240kDa inclusive of tags
• Source: Wheat germ
• Tissue specificity: Ameloblast-specific. Located at the Tomes processes of secretory ameloblasts and in the sheath space between rod-interrod enamel.
• Form: Liquid
• Purity: Proprietary Purification
• Storage buffer: pH: 8.00Constituents:0.3% Glutathione, 0.79% Tris HCl
• Storage: Shipped on dry ice. Upon delivery aliquot and store at -80oC. Avoid freeze / thaw cycles.
• Sequences of amino acids: MSASKIPLFKMKDLILILCLLEMSFAVPFFPQQSGTPGMA SLSLETMRQLGSLQRLNTLSQYSRYGFGKSFNSLWMHGLL PPHSSLPWMRPREHETQQYEYSLPVHPPPLPSQPSLKPQQ PGLKPFLQSAAATTNQATALKEALQPPIHLGHLPLQEGEL PLVQQQVAPSDKPPKPELPGVDFADPQGPSLPGMDFPDPQ GPSLPGLDFADPQGSTIFQIARLISHGPMPQNKQSPLYPG MLYVPFGANQLNAPARLGIMSSEEVAGGREDPMAYGAMFP GFGGMRPGFEGMPHNPAMGGDFTLEFDSPVAATKGPENEE GGAQGSPMPEANPDNLENPAFLTELEPAPHAGLLALPKDD IPGLPRSPSGKMKGLPSVTPAAADPLMTPELADVYRTYDA DMTTSVDFQEEATMDTTMAPNSLQTSMPGNKAQEPEMMHD AWHFQEP
• Sequence Similarities: Belongs to the ameloblastin family.

Gene Information

• Gene Name: AMBN ameloblastin (enamel matrix protein) [ Homo sapiens ]
• Official Symbol: AMBN
• Synonyms: AMBN; ameloblastin (enamel matrix protein); ameloblastin, enamel matrix protein; ameloblastin
• Gene ID: 258
• mRNA Refseq: NM_016519
• Protein Refseq: NP_057603
• MIM: 601259
• Uniprot ID: Q9NP70
• Chromosome Location: 4q21
• Function: growth factor activity; structural constituent of tooth enamel