Recombinant Human CAPN3
Cat.No. : | CAPN3-27402TH |
Product Overview : | Recombinant fragment of Human Calpain 3 with a proprietary tag at the N terminal; Predicted MW 36.63 kDa, inclusive of tag. |
- Specification
- Gene Information
- Related Products
Description : | Calpain, a heterodimer consisting of a large and a small subunit, is a major intracellular protease, although its function has not been well established. This gene encodes a muscle-specific member of the calpain large subunit family that specifically binds to titin. Mutations in this gene are associated with limb-girdle muscular dystrophies type 2A. Alternate promoters and alternative splicing result in multiple transcript variants encoding different isoforms and some variants are ubiquitously expressed. |
Protein length : | 100 amino acids |
Molecular Weight : | 36.630kDa inclusive of tags |
Source : | Wheat germ |
Tissue specificity : | Isoform I is skeletal muscle specific. |
Form : | Liquid |
Purity : | Proprietary Purification |
Storage buffer : | pH: 8.00Constituents:0.3% Glutathione, 0.79% Tris HCl |
Storage : | Shipped on dry ice. Upon delivery aliquot and store at -80oC. Avoid freeze / thaw cycles. |
Sequences of amino acids : | NKIKAWQKIFKHYDTDQSGTINSYE MRNAVNDAGFHLNNQLYDIITMRYA DKHMNIDFDSFICCFVRLEGMFRAF HAFDKDGDGIIKLNVLEWLQLTMYA |
Sequence Similarities : | Belongs to the peptidase C2 family.Contains 1 calpain catalytic domain.Contains 4 EF-hand domains. |
Gene Name : | CAPN3 calpain 3, (p94) [ Homo sapiens ] |
Official Symbol : | CAPN3 |
Synonyms : | CAPN3; calpain 3, (p94); LGMD2, LGMD2A; calpain-3; CANP3; nCL 1; p94; |
Gene ID : | 825 |
mRNA Refseq : | NM_000070 |
Protein Refseq : | NP_000061 |
MIM : | 114240 |
Uniprot ID : | P20807 |
Chromosome Location : | 15q15.1 |
Pathway : | Integrin-mediated cell adhesion, organism-specific biosystem; TNF-alpha/NF-kB Signaling Pathway, organism-specific biosystem; |
Function : | calcium ion binding; calcium-dependent cysteine-type endopeptidase activity; cysteine-type peptidase activity; peptidase activity; signal transducer activity; |
Products Types
◆ Recombinant Protein | ||
CAPN3-786R | Recombinant Rat CAPN3 Protein, His (Fc)-Avi-tagged | +Inquiry |
CAPN3-22H | Active Recombinant Human CAPN3 Protein, His-tagged | +Inquiry |
CAPN3-107C | Recombinant Cynomolgus Monkey CAPN3 Protein, His (Fc)-Avi-tagged | +Inquiry |
CAPN3-359C | Recombinant Cynomolgus CAPN3 Protein, His-tagged | +Inquiry |
CAPN3-263H | Recombinant Human CAPN3 protein, His-tagged | +Inquiry |
◆ Lysates | ||
CAPN3-7862HCL | Recombinant Human CAPN3 293 Cell Lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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