Recombinant Human COL3A1
Cat.No. : | COL3A1-28012TH |
Product Overview : | Recombinant Full-length Human Collagen-III : the human proalpha1 (III) and both alpha and beta subunits of prolyl hydroxylase were co-expressed in the yeast Pichia pastoris. Procollagen III was converted into mature collagen by a controlled proteinase dig |
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Description : | This gene encodes the pro-alpha1 chains of type III collagen, a fibrillar collagen that is found in extensible connective tissues such as skin, lung, uterus, intestine and the vascular system, frequently in association with type I collagen. Mutations in this gene are associated with Ehlers-Danlos syndrome types IV, and with aortic and arterial aneurysms. Two transcripts, resulting from the use of alternate polyadenylation signals, have been identified for this gene. |
Form : | Liquid |
Purity : | >95% by SDS-PAGE |
Storage buffer : | Component: 10mM HClPreservatives: none. |
Storage : | Store at +4°C. |
Gene Name : | COL3A1 collagen, type III, alpha 1 [ Homo sapiens ] |
Official Symbol : | COL3A1 |
Synonyms : | COL3A1; collagen, type III, alpha 1; EDS4A, Ehlers Danlos syndrome type IV, autosomal dominant; collagen alpha-1(III) chain; |
Gene ID : | 1281 |
mRNA Refseq : | NM_000090 |
Protein Refseq : | NP_000081 |
MIM : | 120180 |
Uniprot ID : | P02461 |
Chromosome Location : | 2q32.2 |
Pathway : | Amoebiasis, organism-specific biosystem; Amoebiasis, conserved biosystem; Axon guidance, organism-specific biosystem; Developmental Biology, organism-specific biosystem; ECM-receptor interaction, organism-specific biosystem; |
Function : | SMAD binding; extracellular matrix structural constituent; integrin binding; integrin binding; platelet-derived growth factor binding; |
Products Types
◆ Recombinant Protein | ||
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COL3A1-786R | Recombinant Rhesus Macaque COL3A1 Protein, His (Fc)-Avi-tagged | +Inquiry |
COL3A1-2793H | Recombinant Human COL3A1 Protein, His-tagged | +Inquiry |
COL3A1-1650H | Recombinant Human COL3A1 Protein, GST-tagged | +Inquiry |
COL3A1-1179R | Recombinant Rat COL3A1 Protein, His (Fc)-Avi-tagged | +Inquiry |
◆ Native Protein | ||
COL3A1-001H | Native Human COL3A1 Protein | +Inquiry |
COL3A1-18B | Native Bovine COL3A1 Protein | +Inquiry |
COL3A1-17B | Native Bovine COL3A1 Protein | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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Q&As (5)
Ask a questionUnderstanding the specific genetic and protein alterations in vEDS patients can help tailor individualized treatment strategies based on the patient's unique molecular profile.
Yes, analysis of COL3A1 protein levels in prenatal samples may provide valuable information for assessing the risk of vEDS in the developing fetus.
Elevated or decreased levels of COL3A1 protein may serve as potential biomarkers for early detection and risk assessment of vEDS, especially in at-risk individuals or families.
Challenges include the need for standardized assays and reference ranges for COL3A1 protein levels, as well as the interpretation of results in the context of individual patient variability.
Yes, monitoring changes in COL3A1 protein levels may provide insights into disease progression and response to treatment in vEDS patients.
Customer Reviews (3)
Write a reviewThis protein demonstrates great performance in WB assays, providing accurate and reliable results that are crucial for protein analysis.
The COL3A1 protein is of exceptional quality, making it an ideal choice to meet my experimental needs.
the COL3A1 protein has proven to be an invaluable tool in protein electron microscopy (EM) structure analysis.
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