Recombinant Human DDC
Cat.No. : | DDC-28085TH |
Product Overview : | Recombinant full length protein (Human) |
- Specification
- Gene Information
- Related Products
Description : | The encoded protein catalyzes the decarboxylation of L-3,4-dihydroxyphenylalanine (DOPA) to dopamine, L-5-hydroxytryptophan to serotonin and L-tryptophan to tryptamine. Defects in this gene are the cause of aromatic L-amino-acid decarboxylase deficiency (AADCD). AADCD deficiency is an inborn error in neurotransmitter metabolism that leads to combined serotonin and catecholamine deficiency. Multiple alternatively spliced transcript variants encoding different isoforms have been identified for this gene. |
Source : | E. coli |
Form : | Liquid |
Purity : | >95% by SDS-PAGE |
Storage buffer : | Preservative: NoneConstituents: 20% Glycerol, 50mM Tris acetate, 1mM EDTA, pH 7.5 |
Storage : | Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles. |
Sequence Similarities : | Belongs to the group II decarboxylase family. |
Gene Name : | DDC dopa decarboxylase (aromatic L-amino acid decarboxylase) [ Homo sapiens ] |
Official Symbol : | DDC |
Synonyms : | DDC; dopa decarboxylase (aromatic L-amino acid decarboxylase); aromatic-L-amino-acid decarboxylase; AADC; |
Gene ID : | 1644 |
mRNA Refseq : | NM_001242889 |
Protein Refseq : | NP_001229818 |
MIM : | 107930 |
Uniprot ID : | P20711 |
Chromosome Location : | 7p11 |
Pathway : | Amine-derived hormones, organism-specific biosystem; Biogenic Amine Synthesis, organism-specific biosystem; Catecholamine biosynthesis, organism-specific biosystem; Catecholamine biosynthesis, tyrosine => dopamine => |
Function : | amino acid binding; aromatic-L-amino-acid decarboxylase activity; aromatic-L-amino-acid decarboxylase activity; lyase activity; protein binding; |
Products Types
◆ Recombinant Protein | ||
DDC-0240H | Recombinant Human DDC Protein (M1-E480), Tag Free | +Inquiry |
Ddc-2490M | Recombinant Mouse Ddc Protein, Myc/DDK-tagged | +Inquiry |
DDC-731H | Recombinant Human DDC Protein, His (Fc)-Avi-tagged | +Inquiry |
Ddc-1322M | Recombinant Mouse Ddc Protein, His-tagged | +Inquiry |
DDC-284H | Active Recombinant Human DDC protein(Met1-Glu480), His-tagged | +Inquiry |
◆ Lysates | ||
DDC-513MCL | Recombinant Mouse DDC cell lysate | +Inquiry |
DDC-724HCL | Recombinant Human DDC cell lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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