Recombinant Human IRF6
Cat.No. : | IRF6-28727TH |
Product Overview : | Recombinant fragment of Human IRF6 with N-terminal proprietary tag. Predicted MW 36.63kDa. |
- Specification
- Gene Information
- Related Products
Description : | This gene encodes a member of the interferon regulatory transcription factor (IRF) family. Family members share a highly-conserved N-terminal helix-turn-helix DNA-binding domain and a less conserved C-terminal protein-binding domain. The encoded protein may be a transcriptional activator. Mutations in this gene can cause van der Woude syndrome and popliteal pterygium syndrome. Mutations in this gene are also associated with non-syndromic orofacial cleft type 6. Alternate splicing results in multiple transcript variants. |
Protein length : | 100 amino acids |
Molecular Weight : | 36.630kDa inclusive of tags |
Source : | Wheat germ |
Tissue specificity : | Expressed in normal mammary epithelial cells. Expression is reduced or absent in breast carcinomas. |
Form : | Liquid |
Purity : | Proprietary Purification |
Storage buffer : | pH: 8.00Constituents:0.3% Glutathione, 0.79% Tris HCl |
Storage : | Shipped on dry ice. Upon delivery aliquot and store at -80oC. Avoid freeze / thaw cycles. |
Sequences of amino acids : | PFEIYLCFGEEWPDGKPLERKLILV QVIPVVARMIYEMFSGDFTRSFDSG SVRLQISTPDIKDNIVAQLKQLYRI LQTQESWQPMQPTPSMQLPPALPPQ |
Sequence Similarities : | Belongs to the IRF family.Contains 1 IRF tryptophan pentad repeat DNA-binding domain. |
Gene Name : | IRF6 interferon regulatory factor 6 [ Homo sapiens ] |
Official Symbol : | IRF6 |
Synonyms : | IRF6; interferon regulatory factor 6; LPS, Van der Woude syndrome , VWS; OFC6; VWS1; |
Gene ID : | 3664 |
mRNA Refseq : | NM_001206696 |
Protein Refseq : | NP_001193625 |
MIM : | 607199 |
Uniprot ID : | O14896 |
Chromosome Location : | 1q32.2-q32.3 |
Pathway : | Apoptosis, organism-specific biosystem; Cytokine Signaling in Immune system, organism-specific biosystem; Immune System, organism-specific biosystem; Interferon Signaling, organism-specific biosystem; Interferon alpha/beta signaling, organism-specific biosystem; |
Function : | DNA binding; protein binding; regulatory region DNA binding; sequence-specific DNA binding transcription factor activity; |
Products Types
◆ Recombinant Protein | ||
IRF6-5035H | Recombinant Human IRF6 Protein, GST-tagged | +Inquiry |
IRF6-4605M | Recombinant Mouse IRF6 Protein, His (Fc)-Avi-tagged | +Inquiry |
IRF6-2120R | Recombinant Rhesus Macaque IRF6 Protein, His (Fc)-Avi-tagged | +Inquiry |
IRF6-1199H | Recombinant Human IRF6 Protein, His (Fc)-Avi-tagged | +Inquiry |
Irf6-3577M | Recombinant Mouse Irf6 Protein, Myc/DDK-tagged | +Inquiry |
◆ Lysates | ||
IRF6-5161HCL | Recombinant Human IRF6 293 Cell Lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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